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Replisome dysfunction upon inducible TIMELESS degradation synergizes with ATR inhibition to trigger replication catastrophe
Authors: Jinal A Patel, Camryn Zezelic, Julie Rageul, Joanne Saldanha, Arafat Khan, Hyungjin Kim
Journal: Nucleic Acids Research
PubMed ID: 37144518
Doi: 10.1093/nar/gkad363
Products & Services: ORF cDNA Clones/MolecularCloud   
Characterization of the conserved features of the NSE6 subunit of the Physcomitrium patens SMC5/6 complex
Authors: Edit Lelkes , Jitka Jemelková , Marcela Holá , Barbora Štefanovie , Peter Kolesár , Radka Vágnerová , Eva Dvořák Tomaštíková , Ales Pecinka , Karel J Angelis , Jan J Paleček
Journal: Plant J .
PubMed ID: 37191775
Doi: 10.1111/tpj.16282
Products & Services: Gene Synthesis   
13C Electron Nuclear Double Resonance Spectroscopy-Guided Molecular Dynamics Computations Reveal the Structure of the Enzyme–Substrate Complex of an Active, N-Linked Glycosylated Lipoxygenase
Authors: Ajay Sharma , Chris Whittington , Mohammed Jabed , S Gage Hill , Anastasiia Kostenko , Tao Yu , Pengfei Li , Peter E Doan , Brian M Hoffman , Adam R Offenbacher
Journal: Biochemistry .
PubMed ID: 37115010
Doi: 10.1021/acs.biochem.3c00119
Products & Services: Gene Synthesis   
A cryo-EM structure of KTF1-bound polymerase V transcription elongation complex
Authors: Hong-Wei Zhang, Kun Huang, Zhan-Xi Gu, Xiao-Xian Wu, Jia-Wei Wang, Yu Zhang
Journal: Nat Commun .
PubMed ID: 37253723
Doi: 10.1038/s41467-023-38619-x
Products & Services: Proteins, Expression, Isolation and Analysis   
Antibacterial mechanism of the novel antimicrobial peptide Jelleine-Ic and its efficacy in controlling Pseudomonas syringae pv actinidiae in kiwifruit
Authors: Mingyu Zhang, Lifang Wang, Wei Tang, Yue Xing, Pu Liu, Xiangli Dang
Journal: Pest Manag Sci
PubMed ID: 37184207
Doi: 10.1002/ps.7548
Products & Services: Molecular Biology Reagents   
Inositol pyrophosphates activate the vacuolar transport chaperone complex in yeast by disrupting a homotypic SPX domain interaction
Authors: Joka Pipercevic, Bastian Kohl, Ruta Gerasimaite, Véronique Comte-Miserez, Sarah Hostachy, Thomas Müntener, Elia Agustoni, Henning Jacob Jessen, Dorothea Fiedler, Andreas Mayer, Sebastian Hiller
Journal: Nat Commun
PubMed ID: 37156835
Doi: 10.1038/s41467-023-38315-w
Products & Services: Molecular Biology Reagents   
Small-Molecule-Mediated Stabilization of PP2A Modulates the Homologous Recombination Pathway and Potentiates DNA Damage-Induced Cell Death
Authors: Rita A Avelar, Amy J Armstrong, Gracie Carvette, Riya Gupta, Noah Puleo, Jose A Colina, Peronne Joseph, Alexander M Sobeck, Caitlin M O'Connor, Brynne Raines, Agharnan Gandhi, Michele L Dziubinski, Daniel S Ma, Kimberly Resnick, Sareena Singh, Kristine Zanotti, Christa Nagel, Steven Waggoner, Daffyd G Thomas, Stephanie L Skala, Junran Zhang, Goutham Narla, Analisa DiFeo
Journal: Mol Cancer Ther
PubMed ID: 36788429
Doi: 10.1158/1535-7163.MCT-21-0880
Products & Services: CRISPR Plasmids   
Validation of immunoassays for the Chlamydia trachomatis antigen Pgp3 using a chimeric monoclonal antibody
Authors: Brook Goodhew, Xiaoling Tang, Jason Goldstein, Joo Lee, Diana Martin, Sarah Gwyn
Journal: Sci Rep
PubMed ID: 37142607
Doi: 10.1038/s41598-023-33834-4
Products & Services: Proteins, Expression, Isolation and Analysis   
In-cell kinetic stability is an essential trait in metallo-β-lactamase evolution
Authors: Lisandro J González, Guillermo Bahr, Mariano M González, Robert A Bonomo, Alejandro J Vila
Journal: Nat Chem Biol
PubMed ID: 37188957
Doi: 10.1038/s41589-023-01319-0
Products & Services: Gene Synthesis   
Electronegative clusters modulate folding status and RNA binding of unstructured RNA-binding proteins
Authors: Steve Zaharias, Talia Fargason, Rory Greer, Yuhua Song, Jun Zhang
Journal: Protein Sci
PubMed ID: 37060324
Doi: 10.1002/pro.4643
Products & Services: Gene Synthesis   

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