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Drug repurposing screens identify compounds that inhibit α-synuclein oligomers' membrane disruption and block antibody interactions
Authors: Arun Kumar Somavarapu, Giulia Kleijwegt, Madhu Nagaraj, Parvez Alam, Janni Nielsen, Daniel E Otzen
Journal: Chem Sci
PubMed ID: 36937574
Doi: 10.1039/d2sc05534a
Products & Services: Recombinant Proteins   
A rapid nucleic acid detection platform based on phosphorothioate-DNA and sulfur binding domain
Authors: Yuting Shuai, Yi Ju, Yuanhang Li, Dini Ma, Lan Jiang, Jingyu Zhang, Gao-Yi Tan, Xueting Liu, Shenlin Wang, Lixin Zhang, Guang Liu
Journal: Synth Syst Biotechnol
PubMed ID: 36875498
Doi: 10.1016/j.synbio.2023.02.002
Cas12a-based one-pot SNP detection with high accuracy
Authors: Hong-Xia Zhang, Caixiang Zhang, Shuhan Lu, Xiaohan Tong, Kun Zhang, Hao Yin, Ying Zhang
Journal: Cell Insight
PubMed ID: 37193068
Doi: 10.1016/j.cellin.2023.100080
Two pan-SARS-CoV-2 nanobodies and their multivalent derivatives effectively prevent Omicron infections in mice
Authors: Honghui Liu, Lili Wu, Bo Liu, Ke Xu, Wenwen Lei, Jianguo Deng, Xiaoyu Rong, Pei Du, Lebing Wang, Dongbin Wang, Xiaolong Zhang, Chao Su, Yuhai Bi, Hua Chen, William J Liu, Jianxun Qi, Qingwei Cui, Shuhui Qi, Ruiwen Fan, Jingkun Jiang, Guizhen Wu, George F Gao, Qihui Wang
Journal: cell reports. medicine
PubMed ID: 36702124
Doi: 10.1016/j.xcrm
Products & Services: Gene Synthesis   
Siglec-9 Restrains Antibody-Dependent Natural Killer Cell Cytotoxicity against SARS-CoV-2
Authors: Pratima Saini, Opeyemi S Adeniji, Devivasha Bordoloi, Jennifer Kinslow, Jeff Martinson, Danielle M Parent, Kai Ying Hong, Jane Koshy, Abhijeet J Kulkarni, Netanel F Zilberstein, Robert A Balk, James N Moy, Leila B Giron, Russell P Tracy, Ali Keshavarzian, Kar Muthumani, Alan Landay, David B Weiner, Mohamed Abdel-Mohsen
Journal: MBio
PubMed ID: 36728420
Doi: 10.1128/mbio.03393-22
Cathepsin H and cathepsin B of Cynoglossus semilaevis are involved in anti-bacterial immunity against Edwardsiella tarda
Authors: Yilong Wang, Hang Xu, Boguang Sun
Journal: Fish Shellfish Immunol
PubMed ID: 36754156
Doi: 10.1016/j.fsi.2023.108594
Molecular basis of RADAR anti-phage supramolecular assemblies
Authors: Yina Gao, Xiu Luo, Peipei Li, Zhaolong Li, Feng Ye, Songqing Liu, Pu Gao
Journal: Cell
PubMed ID: 36764292
Doi: 10.1016/j.cell.2023.01.026
Insights into the oligomeric structure of the HIV-1 Vpu protein
Authors: Saman Majeed, Oluwatosin Adetuyi, Peter P Borbat, Md Majharul Islam, Olamide Ishola, Bo Zhao, Elka R Georgieva
Journal: J Struct Biol
PubMed ID: 36796461
Doi: 10.1016/j.jsb.2023.107943
Products & Services: Molecular Biology Reagents   
Engineered antibody cytokine chimera synergizes with DNA-launched nanoparticle vaccines to potentiate melanoma suppression
Authors: Nicholas J Tursi, Ziyang Xu, Michaela Helble, Susanne Walker, Kevin Liaw, Neethu Chokkalingam, Toshitha Kannan, Yuanhan Wu, Edgar Tello-Ruiz, Daniel H Park, Xizhou Zhu, Megan C Wise, Trevor R F Smith, Sonali Majumdar, Andrew Kossenkov, Daniel W Kulp, David B Weiner
Journal: Front Immunol
PubMed ID: 36911698
Doi: 10.3389/fimmu.2023.1072810
Products & Services: Molecular Biology Reagents   
Transcriptional dynamics of maize leaves, pollens and ovules to gain insights into heat stress-related responses
Authors: Ashok Babadev Jagtap, Inderjit Singh Yadav, Yogesh Vikal, Umesh Preethi Praba, Navneet Kaur, Adeshpal Singh Gill, Gurmukh S Johal
Journal: Front Plant Sci
PubMed ID: 36875566
Doi: 10.3389/fpls.2023.1117136
Products & Services: PCR Cloning and Subcloning   

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