| Epitope |
| Clone | Epitope mapping |
|---|
| 25G13 | 33-42 | | 6E8 | 1-7 | | A40 | 35-40 |
|
| Specificity |
| Substance | 25G13 | 6E8 | A40 |
|---|
| Beta-amyloid (1-42) | + | + | - | | Beta-amyloid (1-40) | - | + | + | | Amyloid precursor protein | - | - | - |
Note:”+” means reaction, “-“ means no cross-reactivity
|
| Isotype |
IgG2a for mAb 25G13; IgG2b for mAb 6E8
IgG1 for mAb A40
|
| Production |
Cultured in vitro under conditions free from animal-derived components
|
| Purification |
Protein A/G affinity column
|
| Formulation |
50 mM Na-citrate, 150 mM NaCl, pH 7.0, containing 0.03% Proclin 300
|
| Storage |
For up to three months at 2-8°C or for up to three years at -25°C~-15°C.
Avoid repeated freezing and thawing.
|
| Note |
GenScript can customize this product per customer's request including
product size, buffer components, etc.
|
| Platform |
Capture |
Detection |
Analyte |
| CLIA |
6E8 |
25G13 |
Beta-amyloid 1-42 |
|
A40 |
6E8 |
Beta-amyloid 1-40 |
|
| Target Background |
Beta-amyloid (Aβ or Abeta) are peptides of 36–43 amino acids. They are derived from the amyloid precursor protein (APP) by beta secretase and
gamma secretase in human brain. Beta-amyloid 1-42 and Beta-amyloid 1-
40 are related to Alzheimer's disease (AD).
|
For laboratory research use only. Direct human use, including taking orally and injection and clinical use are
forbidden.
