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Structure-based design of non-natural amino-acid inhibitors of amyloid fibril formation.
  • Sievers SA, Karanicolas J, Chang HW, Zhao A, Jiang L, Zirafi O, Stevens JT, Münch J, Baker D, Eisenberg D.
  • Nature. 2011 Jun; 475 (7354); 96-100
Immune Self-Reactivity Triggered By Drug-Modified Hla-Peptide Repertoire.
  • Illing PT, Vivian JP, Dudek NL, Kostenko L, Chen Z, Bharadwaj M, Miles JJ, Kjer-Nielsen L, Gras S, Williamson NA, Burrows SR, Purcell AW, Rossjohn J, McCluskey J.
  • Nature. 2012 Jun;
How insulin engages its primary binding site on the insulin receptor.
  • John G. Menting, Jonathan Whittaker, Mai B. Margetts, Linda J. Whittaker, Geoffrey K.-W. Kong, + et al.
  • Nature. 2013 Jan;
Mechanism of Trypanosoma brucei gambiense resistance to human serum.
  • Uzureau P, Uzureau S, Lecordier L, Fontaine F, Tebabi P, HomblÉ F, GrÉlard A, Zhendre V, Nolan DP, Lins L, Crowet JM, Pays A, Felu C, Poelvoorde P, Vanhollebeke B, Moestrup SK, Lyngsø J, Pedersen JS, Mottram JC, Dufourc EJ, PÉrez-Morga D, Pays E.
  • Nature. 2013 Aug;
Signal peptides are allosteric activators of the protein translocase.
  • Gouridis G, Karamanou S, Gelis I, Kalodimos CG, Economou A.
  • Nature. 2009 Nov; 462 (7271); 363-7
NRMT is an [agr]-N-methyltransferase that methylates RCC1 and retinoblastoma protein.
  • Tooley CE, Petkowski JJ, Muratore-Schroeder TL, Balsbaugh JL, Shabanowitz J, Sabat M, Minor W, Hunt DF, Macara IG.
  • Nature. 2010 Aug; 466 (7310); 1125-8
Cross-neutralization of influenza A viruses mediated by a single antibody loop.
  • Ekiert DC, Kashyap AK, Steel J, Rubrum A, Bhabha G, Khayat R, Lee JH, Dillon MA, O'Neil RE, Faynboym AM, Horowitz M, Horowitz L, Ward AB, Palese P, Webby R, Lerner RA, Bhatt RR, Wilson IA.
  • Nature. 2012 Sep; 489 (7417); 526-32
A peptide deformylase-ribosome complex reveals mechanism of nascent chain processing.
  • Bingel-Erlenmeyer R, Kohler R, Kramer G, Sandikci A, Antolic S, Maier T, Schaffitzel C, Wiedmann B, Bukau B, Ban N.
  • Nature. 2008 Apr; 452 (7183); 108-11
An aspartyl protease directs malaria effector proteins to the host cell.
  • Boddey JA, Hodder AN, GÜnther S, Gilson PR, Patsiouras H, Kapp EA, Pearce JA, de Koning-Ward TF, Simpson RJ, Crabb BS, Cowman AF.
  • Nature. 2010 Feb; 463 (7281); 627-31
A conformational switch in HP1 releases auto-inhibition to drive heterochromatin assembly.
  • Canzio D, Liao M, Naber N, Pate E, Larson A, Wu S, Marina DB, Garcia JF, Madhani HD, Cooke R, Schuck P, Cheng Y, Narlikar GJ.
  • Nature. 2013 Apr; 496 (7445); 377-81
Many X-linked microRNAs escape meiotic sex chromosome inactivation.
  • Song R, Ro S, Michaels JD, Park C, McCarrey JR, Yan W.
  • Nat Genet. 2009 Apr; 41 (4); 488-93
Mutations in TMEM216 perturb ciliogenesis and cause Joubert, Meckel and related syndromes.
  • Valente EM, Logan CV, Mougou-Zerelli S, Lee JH, Silhavy JL, Brancati F, Iannicelli M, Travaglini L, Romani S, Illi B, Adams M, Szymanska K. 查看更多 »Mazzotta A, Lee JE, Tolentino JC, Swistun D, Salpietro CD, Fede C, Gabriel S, Russ C, Cibulskis K, Sougnez C, Hildebrandt F, Otto EA, Held S, Diplas BH, Davis EE, Mikula M, Strom CM, Ben-Zeev B, Lev D, Sagie TL, Michelson M, Yaron Y, Krause A, Boltshauser E, Elkhartoufi N, Roume J, Shalev S, Munnich A, Saunier S, Inglehearn C, Saad A, Alkindy A, Thomas S, Vekemans M, Dallapiccola B, Katsanis N, Johnson CA, AttiÉ-Bitach T, Gleeson JG.
  • Nat Genet. 2010 Jul; 42 (7); 619-252
Reversible active switching of the mechanical properties of a peptide film at a fluid-fluid interface.
  • Dexter AF, Malcolm AS, Middelberg AP.
  • Nat Mater. 2006 Jun; 5 (6); 502-506
DNA Damage in Oocytes Induces a Switch of the Quality Control Factor TAp63α from Dimer to Tetramer.
  • Deutsch GB, Zielonka EM, Coutandin D, Weber TA, Schäfer B, Hannewald J, Luh LM, Durst FG, Ibrahim M, Hoffmann J, Niesen FH, Sentürk A, Kunkel H, Brutschy B, Schleiff E, Knapp S, Acker-Palmer A, Grez M, McKeon F, Dötsch V.
  • Cell. 2011 Feb; 144 (4); 566 - 576
Order Out Of Disorder: Working Cycle Of An Intrinsically Unfolded Chaperone.
  • Reichmann D, Xu Y, Cremers CM, Ilbert M, Mittelman R, Fitzgerald MC, Jakob U.
  • Cell. 2012 Mar; 148 (5); 947-57
aPKC Phosphorylation of Bazooka Defines the Apical/Lateral Border in Drosophila; Epithelial Cells.
  • Morais-de-SÁ E, Mirouse V, St Johnston D.
  • Cell. 2010 Apr; 141 (3); 509-23
Influenza virus M2 protein mediates ESCRT-independent membrane scission.
  • Rossman JS, Jing X, Leser GP, Lamb RA.
  • Cell. 2010 Sep; 142 (6); 902-13
Kinetics of antimicrobial peptide activity measured on individual bacterial cells using high-speed atomic force microscopy.
  • Fantner GE, Barbero RJ, Gray DS, Belcher AM.
  • Nat Nanotechnol. 2010 Apr; 5 (4); 280-5
A novel Minimalist Cell-Free MHC Class II Antigen Processing System Identifies Immunodominant Epitopes.
  • Hartman IZ, Kim A, Cotter RJ, Walter K, Dalai SK, Boronina T, Griffith W, Lanar DE, Schwenk R, Krzych U, Cole RN, Sadegh-Nasseri S.
  • Nat Med. 2010 Nov; 16 (11); 1333-40

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