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Biosynthesis of valerenic acid by engineered Saccharomyces cerevisiae
Authors: Mengya Zhao, Chuanbo Zhang, Haibin Wang, Shifan He, Wenyu Lu
Journal: Biotechnol Lett
PubMed ID: 35643816
Doi: 10.1007/s10529-022-03264-9
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Atomic-Resolution Structure of SARS-CoV-2 Nucleocapsid Protein N-Terminal Domain
Authors: Sucharita Sarkar, Brent Runge, Ryan W Russell, Kumar Tekwani Movellan, Daniel Calero, Somayeh Zeinalilathori, Caitlin M Quinn, Manman Lu, Guillermo Calero, Angela M Gronenborn, Tatyana Polenova
Journal: J Am Chem Soc
PubMed ID: 35638584
Doi: 10.1021/jacs.2c03320
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Structural basis for the synthesis of the core 1 structure by C1GalT1
Authors: Andrés Manuel González-Ramírez, Ana Sofia Grosso, Zhang Yang, Ismael Compañón, Helena Coelho, Yoshiki Narimatsu, Henrik Clausen, Filipa Marcelo, Francisco Corzana, Ramon Hurtado-Guerrero
Journal: Nat Commun
PubMed ID: 35504880
Doi: 10.1038/s41467-022-29833-0
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Furin and TMPRSS2 Resistant Spike Induces Robust Humoral and Cellular Immunity Against SARS-CoV-2 Lethal Infection
Authors: Jhe-Jhih Lin, Chih-Feng Tien, Yi-Ping Kuo, En-Ju Lin, Wei-Hsiang Tsai, Ming-Yu Chen, Pei-Ju Tsai, Yu-Wen Su, Nikhil Pathak, Jinn-Moon Yang, Chia-Yi Yu, Zih-Shiuan Chuang, Han-Chieh Wu, Wan-Ting Tsai, Shih-Syong Dai, Hung-Chun Liao, Kit Man Chai, Yu-Siang Su, Tsung-Hsien Chuang, Shih-Jen Liu, Hsin-Wei Chen, Horng-Yunn Dou, Feng-Jui Chen, Chiung-Tong Chen, Chin-Len Liao, Guann-Yi Yu
Journal: Front Immunol
PubMed ID: 35585971
Doi: 10.3389/fimmu.2022.872047
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L-tyrosine-bound ThiH structure reveals C-C bond break differences within radical SAM aromatic amino acid lyases
Authors: Patricia Amara, Claire Saragaglia, Jean-Marie Mouesca, Lydie Martin, Yvain Nicolet
Journal: Nat Commun
PubMed ID: 35477710
Doi: 10.1038/s41467-022-29980-4
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Evaluation of biotransformation capacity of transplastomic plants and hairy roots of Nicotiana tabacum expressing human cytochrome P450 2D6
Authors: Y V Sheludko, I M Gerasymenko, F J Herrmann, H Warzecha
Journal: Transgenic Res
PubMed ID: 35416604
Doi: 10.1007/s11248-022-00305-x
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Novel sarbecovirus bispecific neutralizing antibodies with exceptional breadth and potency against currently circulating SARS-CoV-2 variants and sarbecoviruses
Authors: Yingdan Wang, Meiqin Liu, Yaping Shen, Yunping Ma, Xiang Li, Yuanyuan Zhang, Mei Liu, Xing-Lou Yang, Jun Chen, Renhong Yan, Die Luan, Yanqun Wang, Ying Chen, Qimin Wang, Haofeng Lin, Yaning Li, Kaiyue Wu, Tongyu Zhu, Jincun Zhao, Hongzhou Lu, Yumei Wen, Shibo Jiang, Fan Wu, Qiang Zhou, Zheng-Li Shi, Jinghe Huang
Journal: Cell Discov
PubMed ID: 35443747
Doi: 10.1038/s41421-022-00401-6
Phospholipids alter activity and stability of mitochondrial membrane-bound ubiquitin ligase MARCH5
Authors: Lisa Merklinger, Johannes Bauer, Per A Pedersen, Rune Busk Damgaard, J Preben Morth
Journal: Life Sci Alliance
PubMed ID: 35459736
Doi: 10.26508/lsa.202101309
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Non-homologous End Joining-Mediated Insertional Mutagenesis Reveals a Novel Target for Enhancing Fatty Alcohols Production in
Authors: Mengxu Li, Jinlai Zhang, Qiuyan Bai, Lixia Fang, Hao Song, Yingxiu Cao
Journal: Front Microbiol
PubMed ID: 35547152
Doi: 10.3389/fmicb.2022.898884
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Metal binding and interdomain thermodynamics of mammalian metallothionein-3: enthalpically favoured Cu supplants entropically favoured Zn to form Cu clusters under physiological conditions
Authors: Matthew R Mehlenbacher, Rahma Elsiesy, Rabina Lakha, Rhiza Lyne E Villones, Marina Orman, Christina L Vizcarra, Gabriele Meloni, Dean E Wilcox, Rachel N Austin
Journal: Chem Sci
PubMed ID: 35655557
Doi: 10.1039/d2sc00676f
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