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至今，GenScript的服务及产品已被Cell, Nature, Science, PNAS等1300多家生物医药类杂志引用近万次，处于行业领先水平。NIH、哈佛、耶鲁、斯坦福、普林斯顿、杜克大学等约400家全球著名机构使用GenScript的基因合成、多肽服务、抗体服务和蛋白服务等成功地发表科研成果，再次证明GenScript 有能力帮助业内科学家Make research easy.

页码: 61/209 每页显示数量

An open-source drug discovery platform enables ultra-large virtual screens.

Authors: Gorgulla C,Boeszoermenyi A,Wang ZF,Fischer PD,Coote PW,Padmanabha Das KM,Malets YS,Radchenko DS,Moroz YS,Scott DA,Fackeldey K,Hoffmann M,Iavniuk I,Wagner G,Arthanari H

Journal: Nature

PubMed ID: 32152607

Doi: 10.1038/s41586-020-2117-z

Products & Services: Codon Optimization

Tick Saliva Protein Evasin-3 Allows for Visualization of Inflammation in Arteries through Interactions with CXC-Type Chemokines Deposited on Activated Endothelium

Authors: Denisov SS, Heinzmann ACA, Vajen T, Vries MHM, Megens RTA, Suylen D, Koenen RR, Post MJ, Ippel JH, Hackeng TM, Dijkgraaf I

Journal: Bioconjug Chem

PubMed ID: 32077689

Doi: 10.1021/acs.bioconjchem.0c00095

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Boceprevir, GC-376, and calpain inhibitors II, XII inhibit SARS-CoV-2 viral replication by targeting the viral main protease

Authors: Chunlong Ma, Brett Hurst, Yanmei Hu, Tommy Szeto, Bart Tarbet, Jun Wang

Journal: biorxiv

Doi: 10.1101/2020.04.20.051581

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PERK (Protein Kinase RNA-Like ER Kinase) Branch of the Unfolded Protein Response Confers Neuroprotection in Ischemic Stroke by Suppressing Protein Synthesis

Authors: Ya-Chao Wang, Xuan Li, Yuntian Shen, Jingjun Lyu, Huaxin Sheng, Wulf Paschen, Wei Yang

Journal: Stroke

PubMed ID: 32212900

Doi: 10.1161/STROKEAHA.120.029071

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Remdesivir is a direct-acting antiviral that inhibits RNA-dependent RNA polymerase from severe acute respiratory syndrome coronavirus 2 with high potency

Authors: Gordon CJ, Tchesnokov EP, Woolner E, Perry JK, Feng JY, Porter DP, Gotte M

Journal: J Biol Chem

PubMed ID: 32284326

Doi: 10.1074/jbc.RA120.013679

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Structure-Based Design of Prefusion-Stabilized Filovirus Glycoprotein Trimers

Authors: Rutten L, Gilman MSA, Blokland S, Juraszek J, McLellan JS, Langedijk JPM

Journal: Cell Rep

PubMed ID: 32234486

Doi: 10.1016/j.celrep.2020.03.025

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Use of acetate for the production of 3-hydroxypropionic acid by metabolically-engineered Pseudomonas denitrificans

Authors: Shengfang Zhou, Suman Lama, Jihong Jiang, Mugesh Sankaranarayanan, Sunghoon Park

Journal: Bioresour Technol

PubMed ID: 32234590

Doi: 10.1016/j.biortech.2020.123194

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1H-Imidazole-2, 5-Dicarboxamides as NS4A Peptidomimetics: Identification of a New Approach to Inhibit HCV-NS3 Protease

Authors: Omar AM, Elfaky MA, Arold ST, Soror SH, Khayat MT, Asfour HZ, Bamane FH, El-Araby ME

Journal: Biomolecules

PubMed ID: 32245218

Doi: 10.3390/biom10030479.

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A riboswitch gives rise to multi-generational phenotypic heterogeneity in an auxotrophic bacterium

Authors: Jhonatan A Hernandez-Valdes, Jordi van Gestel, Oscar P Kuipers

Journal: Nat Commun

PubMed ID: 32139702

Doi: 10.1038/s41467-020-15017-1

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A Syringe-Based Biosensor to Rapidly Detect Low Levels of Escherichia Coli (ECOR13) in Drinking Water Using Engineered Bacteriophages

Authors: Troy C Hinkley, Spencer Garing, Paras Jain, John Williford, Anne-Laure M Le Ny, Kevin P Nichols, Joseph E Peters, Joey N Talbert, Sam R Nugen

Journal: Sensors (Basel)

PubMed ID: 32244369

Doi: 10.3390/s20071953

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