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Structure and dynamics of a pentameric KCTD5/CUL3/Gβγ E3 ubiquitin ligase complex
Authors: Duc Minh Nguyen, Deanna H Rath, Dominic Devost, Darlaine Pétrin, Robert Rizk, Alan X Ji, Naveen Narayanan, Darren Yong, Andrew Zhai, Douglas A Kuntz, Maha U Q Mian, Neil C Pomroy, Alexander F A Keszei, Samir Benlekbir, Mohammad T Mazhab-Jafari, John L Rubinstein, Terence E Hébert, Gilbert G Privé
Journal: Proc Natl Acad Sci U S A
PubMed ID: 38625940
Doi: 10.1073/pnas.2315018121
Products & Services: Gene Synthesis   
Efficient gene knockout and genetic interaction screening using the in4mer CRISPR/Cas12a multiplex knockout platform
Authors: Nazanin Esmaeili Anvar, Chenchu Lin, Xingdi Ma, Lori L Wilson, Ryan Steger, Annabel K Sangree, Medina Colic, Sidney H Wang, John G Doench, Traver Hart
Journal: Nat Commun
PubMed ID: 38678031
Doi: 10.1038/s41467-024-47795-3
Products & Services: Gene Synthesis   
Hypoxic dental pulp stem cells-released succinate promotes osteoclastogenesis and root resorption
Authors: Andi Yang, Jinmeng Wang, Zhiyu Yang, Lulu Wang, Houxuan Li, Lang Lei
Journal: Int J Med Sci
PubMed ID: 38774749
Doi: 10.7150/ijms.94972
Products & Services: Gene Synthesis   
Unlocking the distinctive enzymatic functions of the early plant biomass deconstructive genes in a brown rot fungus by cell-free protein expression
Authors: Jesus D Castaño, Irina V El Khoury, Joshua Goering, James E Evans, Jiwei Zhang
Journal: Appl Environ Microbiol
PubMed ID: 38567954
Doi: 10.1128/aem.00122-24
Products & Services: Gene Synthesis   
Heterogeneous and Cooperative Rupture of Histidine-Ni Metal-Coordination Bonds on Rationally Designed Protein Templates
Authors: Eesha Khare, Constancio Gonzalez Obeso, Zaira Martín-Moldes, Ayesha Talib, David L Kaplan, Niels Holten-Andersen, Kerstin G Blank, Markus J Buehler
Journal: ACS Biomater Sci Eng
PubMed ID: 38669114
Doi: 10.1021/acsbiomaterials.3c01819
Products & Services: Gene Synthesis   
Identification and characterization of emGalaseE, a β-1,4 galactosidase from Elizabethkingia meningoseptica, and its application on living cell surface
Authors: Yongliang Tong, Xinrong Lu, Danfeng Shen, Lin Rao, Lin Zou, Shaoxian Lyu, Linlin Hou, Guiqin Sun, Li Chen
Journal: Biological Macromolecules
PubMed ID: 38657932
Doi: 10.1016/j.ijbiomac.2024.131766
Products & Services: Gene Synthesis   
Evolutionary analysis reveals the origin of sodium coupling in glutamate transporters
Authors: Krishna D Reddy, Burha Rasool, Farideh Badichi Akher, Nemanja Kutlešić, Swati Pant, Olga Boudker
Journal: biorxiv
PubMed ID: 38106174
Doi: 10.1101/2023.12.03.569786
Products & Services: Gene Synthesis   
Engineered Luminescent Oncolytic Vaccinia Virus Activation of Photodynamic-Immune Combination Therapy for Colorectal Cancer
Authors: Lu-Yi Ye, Yi-Shu Li, Tong Ge, Long-Cai Liu, Jing-Xing Si, Xue Yang, Wei-Jiao Fan, Xiao-Zhen Liu, You-Ni Zhang, Jun-Wei Wang, Shi-Bing Wang, Hai Zou, Yue-Liang Zheng, Ke-Tao Jin, Zheng-Wei Mao, Yu Cai, Xiao-Zhou Mou
Journal: Adv Healthc Mater
PubMed ID: 38551143
Doi: 10.1002/adhm.202304136
Products & Services: Gene Synthesis   
Proteolytic cleavage of the TGFβ co-receptor CD109 changes its conformation, resulting in protease inhibition via activation of its thiol ester, and dissociation from the cell membrane
Authors: Kathrine Tejlgård Jensen, Nadia Sukusu Nielsen, Ana Viana Almeida, Ida B Thøgersen, Jan J Enghild, Seandean Lykke Harwood
Journal: FEBS J
PubMed ID: 38587194
Doi: 10.1111/febs.17128
Products & Services: Gene Synthesis   
YeeD is an essential partner for YeeE-mediated thiosulfate uptake in bacteria and regulates thiosulfate ion decomposition
Authors: Mai Ikei, Ryoji Miyazaki, Keigo Monden, Yusuke Naito, Azusa Takeuchi, Yutaro S Takahashi, Yoshiki Tanaka, Keina Murata, Takaharu Mori, Muneyoshi Ichikawa, Tomoya Tsukazaki
Journal: PLoS Biol
PubMed ID: 38656967
Doi: 10.1371/journal.pbio.3002601
Products & Services: Gene Synthesis   

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