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Integrative high-throughput enhancer surveying and functional verification divulges a YY2-condensed regulatory axis conferring risk for osteoporosis
Authors: Xiao-Feng Chen, Yuan-Yuan Duan, Ying-Ying Jia, Qian-Hua Dong, Wei Shi, Yan Zhang, Shan-Shan Dong, Meng Li, Zhongbo Liu, Fei Chen, Xiao-Ting Huang, Ruo-Han Hao, Dong-Li Zhu, Rui-Hua Jing, Yan Guo, Tie-Lin Yang
Journal: Cell Genom
PubMed ID: 38335956
Doi: 1016/j.xgen.2024.100501
Products & Services: Gene Synthesis   Oligo pool   
Saikosaponin d protects pancreatic acinar cells against cerulein-induced pyroptosis through alleviating mitochondrial damage and inhibiting cGAS-STING pathway
Authors: Hui Chen, Xirong Lu, Beiqi Xu, Gang Cheng, Yuyi Li, Dan Xie
Journal: J Appl Toxicol
PubMed ID: 38462915
Doi: 10.1002/jat.4594
Products & Services: Gene Synthesis   
4'--MethylbavachalconeB Targeted 14-3-3ζ Blocking the Integrin β3 Early Outside-In Signal to Inhibit Platelet Aggregation and Thrombosis
Authors: Ziqi Tang, Fanqi Lin, Zhiwen Chen, Boyang Yu, Ji-Hua Liu, Xiufeng Liu
Journal: J Agric Food Chem
PubMed ID: 38509000
Doi: 10.1021/acs.jafc.3c05211
Products & Services: Gene Synthesis   
Antibody targeting of surface P-selectin glycoprotein ligand 1 leads to lymphoma apoptosis and tumorigenesis inhibition
Authors: João L Pereira, Francisca Ferreira, Nuno R Dos Santos
Journal: Hematol Oncol
PubMed ID: 38415859
Doi: 10.1002/hon.3257
Products & Services: Gene Synthesis   
Study on the Thermal Stability of the Sweet-Tasting Protein Brazzein Based on Its Structure-Sweetness Relationship
Authors: Jingnan Zuo, Wei Zheng, Nian Shi, Rong Song, Fei Han, Chen Yang, Jingwen Li, Chao Peng, Bin Li, Yijie Chen
Journal: J Agric Food Chem
PubMed ID: 38526016
Doi: 10.1021/acs.jafc.3c09616
Products & Services: Gene Synthesis   
ARGLU1 enhances promoter-proximal pausing of RNA polymerase II and stimulates DNA damage repair
Authors: Scott Bachus, Nikolas Akkerman, Lauren Fulham, Drayson Graves, Rafe Helwer, Jordan Rempel, Peter Pelka
Journal: Nucleic Acids Research
PubMed ID: 38520408
Doi: 10.1093/nar/gkae208
Products & Services: Gene Synthesis   
DNA fragility at topologically associated domain boundaries is promoted by alternative DNA secondary structure and topoisomerase II activity
Authors: Heather M Raimer Young, Pei-Chi Hou, Anna R Bartosik, Naomi D Atkin, Lixin Wang, Zhenjia Wang, Aakrosh Ratan, Chongzhi Zang, Yuh-Hwa Wang
Journal: Nucleic Acids Research
PubMed ID: 38452213
Doi: 10.1093/nar/gkae164
Products & Services: Gene Synthesis   
Humanin variant P3S is associated with longevity in APOE4 carriers and resists APOE4-induced brain pathology
Authors: Brendan Miller, Su-Jeong Kim, Kevin Cao, Hemal H Mehta, Neehar Thumaty, Hiroshi Kumagai, Tomomitsu Iida, Cassandra McGill, Christian J Pike, Kamila Nurmakova, Zachary A Levine, Patrick M Sullivan, Kelvin Yen, Nilüfer Ertekin-Taner, Gil Atzmon, Nir Barzilai, Pinchas Cohen
Journal: Cell
PubMed ID: 38520065
Doi: 10.1111/acel.14153
Products & Services: Gene Synthesis   
CAR-engineered lymphocyte persistence is governed by a FAS ligand/FAS auto-regulatory circuit
Authors: Fei Yi, Tal Cohen, Natalie Zimmerman, Friederike Dündar, Paul Zumbo, Razan Eltilib, Erica J Brophy, Hannah Arkin, Judith Feucht, Michael V Gormally, Christopher S Hackett, Korbinian N Kropp, Inaki Etxeberria, Smita S Chandran, Jae H Park, Katharine C Hsu, Michel Sadelain, Doron Betel, Christopher A Klebanoff
Journal: biorxiv
PubMed ID: 38464085
Doi: 10.1101/2024.02.26.582108
Products & Services: Gene Synthesis   
MicroRNA-223-3p downregulates the inflammatory response in preeclampsia placenta via targeting NLRP3
Authors: Xueqiong Liu, Zhiyue Li, Dan Lu
Journal: BMC Pregnancy Childbirth
PubMed ID: 38448875
Doi: 10.1186/s12884-024-06371-9
Products & Services: Gene Synthesis   

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