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Low intrinsic efficacy for G protein activation can explain the improved side effect profiles of new opioid agonists
Authors: Gillis A, Gondin AB, Kliewer A, Sanchez J, Lim HD, Alamein C, Manandhar P, Santiago M, Fritzwanker S, Schmiedel F, Katte TA, Reekie T, Grimsey NL, Kassiou M, Kellam B, Krasel C, Halls ML, Connor M, Lane JR, Schulz S, Christie MJ, Canals M
Journal: Science Signaling
PubMed ID: 32234959
Doi: 10.1126/scisignal.aaz3140
Products & Services: Gene Synthesis   
Pose Filter-Based Ensemble Learning Enables Discovery of Orally Active, Nonsteroidal Farnesoid X Receptor Agonists
Authors: Xia J,Wang Z,Huan Y,Xue W,Wang X,Wang Y,Liu Z,Hsieh JH,Zhang L,Wu S,Shen Z,Zhang H,Wang XS
Journal: Journal of chemical information and modeling
PubMed ID: 32050066
Doi: 10.1021/acs.jcim.9b01030
Products & Services: Gene Synthesis   
Evaluation of Plasmodium vivax HAP2 as a transmission-blocking vaccine candidate
Authors: Qiu Y, Zhao Y, Liu F, Ye B, Zhao Z, Thongpoon S, Roobsoong W, Sattabongkot J, Cui L, Fan Q, Cao Y
Journal: Vaccine
PubMed ID: 32093983
Doi: 10.1016/j.vaccine.2020.02.011
Products & Services: Gene Synthesis   
Disruption of peroxisome proliferator-activated receptor γ coactivator (PGC)-1α reverts key features of the neoplastic phenotype of glioma cells.
Authors: BrunsInes,SauerBenedikt,BurgerMichael C,ErikssonJule,HofmannUte,BraunYannick,HarterPatrick N,LugerAnna-Luisa,RonellenfitschMichael W,SteinbachJoachim P,RiegerJoha
Journal: J. Biol. Chem.
PubMed ID: 30578297
Doi: 10.1074/jbc.RA118.006993
Products & Services: Gene Synthesis   ORF cDNA Clones/MolecularCloud   
Expression in algae of a chimeric protein carrying several epitopes from tumor associated antigens
Authors: Hernández-Ramírez J, Wong-Arce A, González-Ortega O, Rosales-Mendoza S.
Journal: Int J Biol Macromol
PubMed ID: 31923507
Doi: 10.1016/j.ijbiomac.2019.12.250
Products & Services: Gene Synthesis   
Structure–Activity Relationship Studies on Diversified Salicylamide Derivatives as Potent Inhibitors of Human Adenovirus Infection
Authors: Xu J, Berastegui-Cabrera J, Chen H, Pachón J, Zhou J, Sánchez-Céspedes J
Journal: J Med Chem
PubMed ID: 32045239
Doi: 10.1021/acs.jmedchem.9b01950
Products & Services: Gene Synthesis   
SARS-CoV-2 invades host cells via a novel route: CD147-spike protein
Authors: Ke Wang, Wei Chen, Yu-Sen Zhou, Jian-Qi Lian, Zheng Zhang, Peng Du, Li Gong, Yang Zhang, Hong-Yong Cui, Jie-Jie Geng, Bin Wang, Xiu-Xuan Sun, Chun-Fu Wang, Xu Yang, Peng Lin, Yong-Qiang Deng, Ding Wei, Xiang-Min Yang, Yu-Meng Zhu, Kui Zhang, Zhao-Hui Zheng, Jin-Lin Miao, Ting Guo, Ying Shi, Jun Zhang, Ling Fu, Qing-Yi Wang, Huijie Bian, Ping Zhu, Zhi-Nan Chen
Journal: biorxiv
Doi: 10.1101/2020.03.14.988345
Products & Services: Gene Synthesis   
Microneedle array delivered recombinant coronavirus vaccines: Immunogenicity and rapid translational development
Authors: Kim E, Erdos G, Huang S, Kenniston TW, Balmert SC, Carey CD, Raj VS, Epperly MW, Klimstra WB, Haagmans BL, Korkmaz E, Falo LD Jr, Gambotto A.
Journal: EBioMedicine
Doi: 10.1016/j.ebiom.2020.102743
Products & Services: Gene Synthesis   
Correction: Transgenic overexpression of endogenous FLOWERING LOCUS T-like gene MeFT1 produces early flowering in cassava
Authors:
Journal: PLoS ONE
PubMed ID: 32214391
Doi: 10.1371/journal.pone.0231232
Products & Services: Gene Synthesis   
Dynamics of metal complex binding in relation to catalytic activity and selectivity of an artificial metalloenzyme
Authors: Lara Villarino, Shreyans Chordia, Lur Alonso-Cotchico, Eswar R. Reddem, Andy-Mark Thunnissen, Jean-Didier Maréchal, Gerard Roelfes
Journal: ChemRxiv
Doi: 10.26434/chemrxiv.11969010.v1
Products & Services: Gene Synthesis   

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