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Phylogenetic conservation of Trop-2 across species-rodent and primate genomics model anti-Trop-2 therapy for pre-clinical benchmarks
Authors: Emanuela Guerra, Marco Trerotola, Valeria Relli, Rossano Lattanzio, Khouloud Boujnah, Nicole Travali, Antonino Moschella, Paolo Todaro, Laura Pierdomenico, Roberta Di Pietro, Nicola Tinari, Saverio Alberti
Journal: Front Genet
PubMed ID: 38250577
Doi: 10.3389/fgene.2023.1297367
Products & Services: Gene Synthesis   
Construction and characterization of a humanized rat model with its application in evaluating the uptake of different statins
Authors: Yuanjin Zhang, Junze Huang, Shengbo Huang, Jie Liu, Luyao Deng, Chenmeizi Liang, Yuanqing Guo, Bingyi Yao, Xin Wang
Journal: Acta Pharm Sin B
PubMed ID: 38572097
Doi: 10.1016/j.apsb.2023.12.019
Products & Services: Gene Synthesis   
High-Yield Lasso Peptide Production in a Bacterial Host by Plasmid Copy Number Engineering
Authors: Hannah N Fernandez, Ashley M Kretsch, Sylvia Kunakom, Adjo E Kadjo, Douglas A Mitchell, Alessandra S Eustáquio
Journal: ACS Synth Biol
PubMed ID: 38194362
Doi: 10.1021/acssynbio.3c00597
Products & Services: Gene Synthesis   
PARP1-DNA co-condensation drives DNA repair site assembly to prevent disjunction of broken DNA ends
Authors: Nagaraja Chappidi 1, Thomas Quail 2, Simon Doll 3, Laura T Vogel 4, Radoslav Aleksandrov 5, Suren Felekyan 4, Ralf Kühnemuth 4, Stoyno Stoynov 5, Claus A M Seidel 4, Jan Brugués 6, Marcus Jahnel 3, Titus M Franzmann 1, Simon Alberti
Journal: Cell
PubMed ID: 38320550
Doi: 10.1016/j.cell.2024.01.015
Products & Services: Codon Optimization   Gene Synthesis   
PARP1 condensates differentially partition DNA repair proteins and enhance DNA ligation
Authors: Christopher Chin Sang, Gaelen Moore, Maria Tereshchenko, Michael L Nosella, Hongshan Zhang, T Reid Alderson, Morgan Dasovich, Anthony Leung, Ilya J Finkelstein, Julie D Forman-Kay, Hyun O Lee
Journal: biorxiv
PubMed ID: 38328070
Doi: 10.1101/2024.01.20.575817
Products & Services: Gene Synthesis   
Enantioselective Toxicity and Potential Endocrine-Disruptive Effects of the Insecticides Flufiprole and Ethiprole on
Authors: Lianshan Li, Xuejun Zhao, Kunming Hu, Weiye Xu, Minghua Wang, Hongjie Wang
Journal: J Agric Food Chem
PubMed ID: 38190123
Doi: 10.1021/acs.jafc.3c07896
Products & Services: Gene Synthesis   
Knock-in mutagenesis in Drosophila Rdl underscores the critical role of the conserved M3 glycine in mediating the actions of broflanilide and isocycloseram on GABA receptors
Authors: Yoshihisa Ozoe, Toshifumi Nakao, Shu Kondo, Yasuhide Yoshioka, Fumiyo Ozoe, Shinichi Banba
Journal: Pestic Biochem Physiol
PubMed ID: 38458683
Doi: 10.1016/j.pestbp.2024.105776
Products & Services: Gene Synthesis   
Identification of TMEM126A as OXA1L-interacting protein reveals cotranslational quality control in mitochondria
Authors: Sabine Poerschke, Silke Oeljeklaus, Luis Daniel Cruz-Zaragoza, Alexander Schenzielorz, Drishan Dahal, Hauke Sven Hillen, Hirak Das, Laura Sophie Kremer, Anusha Valpadashi, Mirjam Breuer, Johannes Sattmann, Ricarda Richter-Dennerlein, Bettina Warscheid, Sven Dennerlein, Peter Rehling
Journal: Cell
PubMed ID: 38199007
Doi: 10.1016/j.molcel.2023.12.013
Products & Services: Gene Synthesis   
Molecular mechanism of allosteric activation of the CRISPR ribonuclease Csm6 by cyclic tetra-adenylate
Authors: Liyang Du , Qinwei Zhu & Zhonghui Lin
Journal: The EMBO Journal
Doi: 10.1038/s44318-023-00017-w
Products & Services: Gene Synthesis   
Structural analysis and functional evaluation of the disordered ß–hexosyltransferase region from Hamamotoa (Sporobolomyces) singularis
Authors: Suzanne F Dagher, Asmita Vaishnav, Christopher B Stanley, Flora Meilleur, Brian F P Edwards , José M Bruno-Bárcena
Journal: Front Bioeng Biotechnol
PubMed ID: 38162180
Doi: 10.3389/fbioe.2023.1291245
Products & Services: Gene Synthesis   

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