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Dihydropyridine-derived calcium channel blocker as a promising anti-Hantaviral entry inhibitor
Authors: Bin Wang , Jiawei Pei, Hui Zhang , Jia Li , Yamei Dang , He Liu , Yuan Wang , Liang Zhang , Libin Qi , Yuewu Yang , Linfeng Cheng , Yangchao Dong , Airong Qian , Zhikai Xu , Yingfeng Lei , Fanglin Zhang , Wei Ye
Journal: Front Pharmacol .
PubMed ID: 36105208
Doi: 10.3389/fphar.2022.940178.
Products & Services: Gene Synthesis   
Reduced sister chromatid cohesion acts as a tumor penetrance modifier
Authors: Jun Wang, Holly R Thomas, Yu Chen, Stefanie M Percival, Stephanie C Waldrep, Ryne C Ramaker, Robert G Thompson, Sara J Cooper, Zechen Chong, John M Parant
Journal: PLoS Genet
PubMed ID: 35994499
Doi: 10.1371/journal.pgen.1010341
Products & Services: Gene Synthesis   
Development of a pentavalent broadly protective nucleoside-modified mRNA vaccine against influenza B viruses
Authors: Norbert Pardi, Juan Manuel Carreño, George O'Dell, Jessica Tan, Csaba Bajusz, Hiromi Muramatsu, Willemijn Rijnink, Shirin Strohmeier, Madhumathi Loganathan, Dominika Bielak, Molly M H Sung, Ying K Tam, Florian Krammer, Meagan McMahon
Journal: Nat Commun
PubMed ID: 35945226
Doi: 10.1038/s41467-022-32149-8
Products & Services: Gene Synthesis   
Structural insights into the binding of SARS-CoV-2, SARS-CoV, and hCoV-NL63 spike receptor-binding domain to horse ACE2
Authors: Jun Lan, Peng Chen, Weiming Liu, Wenlin Ren, Linqi Zhang, Qiang Ding, Qi Zhang, Xinquan Wang, Jiwan Ge
Journal: Structure
PubMed ID: 35917815
Doi: 10.1016/j.str.2022.07.005
Products & Services: Gene Synthesis   
High-yield genome engineering in primary cells using a hybrid ssDNA repair template and small-molecule cocktails
Authors: Brian R Shy, Vivasvan S Vykunta, Alvin Ha, Alexis Talbot, Theodore L Roth, David N Nguyen, Wolfgang G Pfeifer, Yan Yi Chen, Franziska Blaeschke, Eric Shifrut, Shane Vedova, Murad R Mamedov, Jing-Yi Jing Chung, Hong Li, Ruby Yu, David Wu, Jeffrey Wolf, Thomas G Martin, Carlos E Castro, Lumeng Ye, Jonathan H Esensten, Justin Eyquem, Alexander Marson
Journal: Nat Biotechnol
PubMed ID: 36008610
Doi: 10.1038/s41587-022-01418-8
Products & Services: Gene Synthesis   
Expedient Synthesis of Ubiquitin-like Protein ISG15 Tools Through Chemo-Enzymatic Ligation Catalyzed by a Viral Protease Lbpro
Authors: Tian Wang , Chuntong Li , Meijing Wang , Jiachen Zhang , Qingyun Zheng , Lujun Liang , Guochao Chu , Xiaolin Tian , Haiteng Deng , Wei He , Lei Liu , Jinghong Li
Journal: Angew Chem Int Ed Engl
PubMed ID: 35962463
Doi: 10.1002/anie.202206205
Products & Services: Gene Synthesis   
Enhancing the Catalytic Activity of Type II L-Asparaginase from Bacillus licheniformis through Semi-Rational Design
Authors: Yawen Zhou ,Linshu Jiao ,Juan Shen ,Huibing Chi ,Zhaoxin Lu ,Huawei Liu ,Fengxia Lu ,Ping Zhu
Journal: Int J Mol Sci
Doi: 10.3390/ijms23179663
Products & Services: Gene Synthesis   
Receptor deorphanization in an echinoderm reveals kisspeptin evolution and relationship with SALMFamide neuropeptides
Authors: Nayeli Escudero Castelán , Dean C Semmens , Luis Alfonso Yañez Guerra , Meet Zandawala , Mario Dos Reis , Susan E Slade , James H Scrivens , Cleidiane G Zampronio , Alexandra M Jones , Olivier Mirabeau , Maurice R Elphick
Journal: BMC Biol
PubMed ID: 36002813
Doi: 10.1186/s12915-022-01387-z
Products & Services: Gene Synthesis   
Membrane transporters control cerebrospinal fluid formation independently of conventional osmosis to modulate intracranial pressure
Authors: Eva K Oernbo, Annette B Steffensen, Pooya Razzaghi Khamesi, Trine L Toft-Bertelsen, Dagne Barbuskaite, Frederik Vilhardt, Niklas J Gerkau, Katerina Tritsaris, Anja H Simonsen, Sara D Lolansen, Søren N Andreassen, Steen G Hasselbalch, Thomas Zeuthen, Christine R Rose, Vartan Kurtcuoglu, Nanna MacAulay
Journal: Fluids Barriers CNS
PubMed ID: 36038945
Doi: 10.1186/s12987-022-00358-4
Products & Services: Gene Synthesis   
Immunogenicity and Protective Efficacy of a Recombinant Pichinde Viral-Vectored Vaccine Expressing Influenza Virus Hemagglutinin Antigen in Pigs
Authors: Sushmita Kumari, Jayeshbhai Chaudhari, Qinfeng Huang, Phillip Gauger, Marcelo Nunes De Almeida, Yuying Liang, Hinh Ly, Hiep L X Vu
Journal: Vaccines (Basel)
PubMed ID: 36146478
Doi: 10.3390/vaccines10091400
Products & Services: Gene Synthesis   

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