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至今，GenScript的服务及产品已被Cell, Nature, Science, PNAS等1300多家生物医药类杂志引用近万次，处于行业领先水平。NIH、哈佛、耶鲁、斯坦福、普林斯顿、杜克大学等约400家全球著名机构使用GenScript的基因合成、多肽服务、抗体服务和蛋白服务等成功地发表科研成果，再次证明GenScript 有能力帮助业内科学家Make research easy.

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Antibody aggregation can lead to reduced Protein A binding capacity and low step yield

Authors: Gaoya Yuan, Meng Qu, Qi Geng, Wanyuan Dong, Xudong Zhang, Yifeng Li

Journal: Protein Expr Purif

PubMed ID: 37271409

Doi: 10.1016/j.pep.2023.106315

Products & Services: Proteins, Expression, Isolation and Analysis

Homology-independent targeted insertion (HITI) enables guided CAR knock-in and efficient clinical scale CAR-T cell manufacturing

Authors: Hyatt Balke-Want, Vimal Keerthi, Nikolaos Gkitsas, Andrew G Mancini, Gavin L Kurgan, Carley Fowler, Peng Xu, Xikun Liu, Kyle Asano, Sunny Patel, Christopher J Fisher, Annie K Brown, Ramya H Tunuguntla, Shabnum Patel, Elena Sotillo, Crystal L Mackall, Steven A Feldman

Journal: Mol Cancer

PubMed ID: 37365642

Doi: 10.1186/s12943-023-01799-7

Products & Services: Proteins, Expression, Isolation and Analysis

Genome-wide characterization of extrachromosomal circular DNA in gastric cancer and its potential role in carcinogenesis and cancer progression

Authors: Xianming Jiang, Xiaoguang Pan, Wenchao Li, Peng Han, Jiaying Yu, Jing Li, Haoran Zhang, Wei Lv, Ying Zhang, Yulong He, Xi Xiang

Journal: Cell Mol Life Sci

PubMed ID: 37369919

Doi: 10.1007/s00018-023-04838-0

Products & Services: Proteins, Expression, Isolation and Analysis

ENPP1 is an innate immune checkpoint of the anticancer cGAMP-STING pathway

Authors: Songnan Wang, Volker Böhnert, Alby J Joseph, Valentino Sudaryo, Jason Swinderman, Feiqiao B Yu, Xuchao Lyu, Gemini Skariah, Vishvak Subramanyam, Luke A Gilbert, Hani Goodarzi, Li Lingyin

Journal: biorxiv

PubMed ID: 37333273

Doi: 10.1101/2023.06.01.543353

Products & Services: Proteins, Expression, Isolation and Analysis

CLDN182 and 4-1BB bispecific antibody givastomig exerts antitumor activity through CLDN182-expressing tumor-directed T-cell activation

Authors: Jing Gao, Zhengyi Wang, Wenqing Jiang, Yanni Zhang, Zhen Meng, Yanling Niu, Zhen Sheng, Chan Chen, Xuejun Liu, Xi Chen, Chanjuan Liu, Keren Jia, Cheng Zhang, Haiyan Liao, Jaeho Jung, Eunsil Sung, Hyejin Chung, Jingwu Z Zhang, Andrew X Zhu, Lin Shen

Journal: J Immunother Cancer

PubMed ID: 37364935

Doi: 10.1136/jitc-2023-006704

Products & Services: Proteins, Expression, Isolation and Analysis

Glutamine synthetase (GS) knockout (KO) using CRISPR/Cpf1 diversely enhances selection efficiency of CHO cells expressing therapeutic antibodies

Authors: Witsanu Srila, Martina Baumann, Markus Riedl, Kuntalee Rangnoi, Nicole Borth, Montarop Yamabhai

Journal: Sci Rep

PubMed ID: 37380701

Doi: 10.1038/s41598-023-37288-6

Products & Services: Proteins, Expression, Isolation and Analysis

Increasing sensitivity of antibody-antigen interactions using photo-cross-linking

Authors: Alba Torrents de la Peña, Leigh M Sewall, Rebeca de Paiva Froes Rocha, Abigail M Jackson, Payal P Pratap, Sandhya Bangaru, Christopher A Cottrell, Subhasis Mohanty, Albert C Shaw, Andrew B Ward

Journal: Cell Rep Methods

PubMed ID: 37426749

Doi: 10.1016/j.crmeth.2023.100509

Products & Services: Proteins, Expression, Isolation and Analysis

The role of mechano-regulated YAP/TAZ in erectile dysfunction

Authors: Mintao Ji, Dongsheng Chen, Yinyin Shu, Shuai Dong, Zhisen Zhang, Haimeng Zheng, Xiaoni Jin, Lijun Zheng, Yang Liu, Yifei Zheng, Wensheng Zhang, Shiyou Wang, Guangming Zhou, Bingyan Li, Baohua Ji, Yong Yang, Yongde Xu, Lei Chang

Journal: Nat Commun

PubMed ID: 37353497

Doi: 10.1038/s41467-023-39009-z

Products & Services: Proteins, Expression, Isolation and Analysis

Preferential rabbit antibody responses to C-termini of NOTCH3 peptide immunogens

Authors: Soo Jung Lee , Mitchell B Gasche , Connor J Burrows , Akhil Kondepudi , Xiaojie Zhang, Michael M Wang

Journal: Sci Rep .

PubMed ID: 37280231

Doi: 10.1038/s41598-023-36067-7

Products & Services: Proteins, Expression, Isolation and Analysis

Cryo-EM structure of SARS-CoV-2 postfusion spike in membrane

Authors: Wei Shi, Yongfei Cai, Haisun Zhu, Hanqin Peng, Jewel Voyer, Sophia Rits-Volloch, Hong Cao, Megan L Mayer, Kangkang Song, Chen Xu, Jianming Lu, Jun Zhang, Bing Chen

Journal: Nature

PubMed ID: 37285872

Doi: 10.1038/s41586-023-06273-4

Products & Services: Proteins, Expression, Isolation and Analysis

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