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Molecular basis of lipid and ligand regulation of prostaglandin receptor DP2

Authors: Jiuyin Xu , Youwei Xu , Li Hou , Xinheng He , Yang Li , Jing Zhao , Xue Meng , James Jiqi Wang , Yanli Wu , Heng Zhang , Yunhai Li , Wen Hu , Qingning Yuan , Kai Wu , Xi Cheng , Yi Jiang , Yu Xia , H Eric Xu , Canrong Wu

Journal: Proc Natl Acad Sci U S A .

PubMed ID: 39665758

Doi: 10.1073/pnas.2403304121

Products & Services: Proteins, Expression, Isolation and Analysis

Multiplexed Assays of Variant Effect and Automated Patch Clamping Improve KCNH2-LQTS Variant Classification and Cardiac Event Risk Stratification

Authors: Matthew J O'Neill, Chai-Ann Ng, Takanori Aizawa, Luca Sala, Sahej Bains, Annika Winbo, Rizwan Ullah, Qianyi Shen, Chek-Ying Tan, Krystian Kozek, Loren R Vanags, Devyn W Mitchell, Alex Shen, Yuko Wada, Asami Kashiwa, Lia Crotti, Federica Dagradi, Giulia Musu, Carla Spazzolini, Raquel Neves, J Martijn Bos, John R Giudicessi, Xavier Bledsoe, Eric R Gamazon, Megan C Lancaster, Andrew M Glazer, Bjorn C Knollmann, Dan M Roden, Jochen Weile, Frederick Roth, Joe-Elie Salem, Nikki Earle, Rachael Stiles, Taylor Agee, Christopher N Johnson, Minoru Horie, Jonathan R Skinner, Michael J Ackerman, Peter J Schwartz, Seiko Ohno, Jamie I Vandenberg, Brett M Kroncke

Journal: Circulation

PubMed ID: 39315434

Doi: 10.1161/CIRCULATIONAHA.124.069828

Products & Services: PCR Cloning and Subcloning

An Oral Nanovaccine Secreted by Genetically Engineered and Ultrasound-Responsive Bacteria for Colon Cancer Immunotherapy

Authors: Jiexin Li, Ruiqi Yang, Yihang Yuan, He Ren, Chao Fang, Jonathan F Lovell, and Yumiao Zhang

Journal: ADV FUNCT MATER

Doi: 10.1002/adfm.202414994

Products & Services: Peptide Synthesis Recombinant Proteins

SPP1+ macrophages promote head and neck squamous cell carcinoma progression by secreting TNF-α and IL-1β

Authors: Chun Liu , Kun Wu , Chuwen Li , Zhen Zhang , Peisong Zhai , Haiyan Guo , Jianjun Zhang

Journal: J Exp Clin Cancer Res

PubMed ID: 39726047

Doi: 10.1186/s13046-024-03255-w

Products & Services: Proteins, Expression, Isolation and Analysis

Dual-Targeted Protein MRI Contrast Agent for Early

Authors: Ruofan Hu, Zhiyang Wang, Tinghui Shen, Qianwen Yang, Weizhi Chen, Xiqun Jiang

Journal: Aggregate

Doi: 10.1002/agt2.732

Products & Services: Proteins, Expression, Isolation and Analysis

Reduced cross-protective potential of Omicron compared to ancestral SARS-CoV-2 spike vaccines against potentially zoonotic coronaviruses.

Authors: Tyler M. Renner, Matthew Stuible, Brian Cass, Sylvie Perret, Julie Guimond, Simon Lord-Dufour, Michael J. McCluskie, Yves Durocher & Bassel Akache

Journal: npj Viruses

Doi: 10.1038/s44298-024-00067-9

Products & Services: Gene Synthesis

Chemoenzymatic Synthesis of the Cyclopiane Family of Diterpenoid Natural Products

Authors: Zhengren Xu, Tao Wang, Jiasheng Zou, Kaibiao Wang, Yuanning Liu, Shouqi Zhang, Yao Kong

Journal: Angew Chem Int Ed Engl

PubMed ID: 39601390

Doi: 10.1002/anie.202419092

Products & Services: Gene Synthesis

An intracellular bacterial pathogen triggers RIG-I/ MDA5-dependent necroptosis

Authors: Hang Xu , Huili Li , Boguang Sun,, Li Sun

Journal: Current Research in Microbial Sciences