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Isofagomine inhibits multiple TcdB variants and protects mice from induced mortality

Authors: Ashleigh S Paparella, Isabella Brew, Huynh A Hong, William Ferriera, Simon Cutting, Farah Lamiable-Oulaidi, Michael Popadynec, Peter C Tyler, Vern L Schramm

Journal: biorxiv

PubMed ID: 37781587

Doi: 10.1101/2023.09.19.558375

Products & Services: Combinatorial DNA Libraries

A temperature dependent pilin promoter for production of thermostable enzymes in Thermus thermophilus

Authors: Lennart Kirchner, Volker Müller, Beate Averhoff

Journal: Microb Cell Fact

PubMed ID: 37726752

Doi: 10.1186/s12934-023-02192-1

Products & Services: Codon Optimization

A Proteorhodopsin-Related Photosensor Expands the Repertoire of Structural Motifs Employed by Sensory Rhodopsins

Authors: Maryam Saliminasab, Yoichi Yamazaki, Alyssa Palmateer, Andrew Harris, Luiz Schubert, Pit Langner, Joachim Heberle, Ana-Nicoleta Bondar, Leonid S Brown

Journal: J Phys Chem B

PubMed ID: 37694950

Doi: 10.1021/acs.jpcb.3c04032

Products & Services: Mutant Libraries Mutagenesis Services Gene Synthesis

RIG-I promotes immune evasion of colon cancer by modulating PD-L1 ubiquitination

Authors: Yangyang Zhang # 1, Lingxiu Zeng # 1, Meng Wang 1, Zhenwei Yang 1, Hailin Z 1, Liping Gao , Ranran Zhang , Jialong Liu , Wenqing Shan , Ying Chang ,Lan Liu , Qiu Zhao , Yong Li , Jing Liu

Journal: J Immunother Cancer .

PubMed ID: 37758653

Doi: 10.1136/jitc-2023-007313

Products & Services: Catalog Peptides

Mechanistic insights into nucleosomal H2B monoubiquitylation mediated by yeast Bre1-Rad6 and its human homolog RNF20/RNF40-hRAD6A

Authors: Zhiheng Deng, Huasong Ai, Maoshen Sun, Zebin Tong, Yunxiang Du, Qian Qu, Liying Zhang, Ziyu Xu, Shixian Tao, Qiang Shi, Jia-Bin Li, Man Pan, Lei Liu

Journal: Mol Cell

PubMed ID: 37633270

Doi: 10.1016/j.molcel.2023.08.001

Products & Services: Proteins, Expression, Isolation and Analysis

Enterococcus faecium C171: Modulating the Immune Response to Acute Lethal Viral Challenge

Authors: Jielan Mi, Tana He, Xinyun Hu, Zhihao Wang, Tingting Wang, Xiaole Qi, Kai Li, Li Gao, Changjun Liu, Yanping Zhang, Suyan Wang, Yu Qiu, Zengqi Liu, Jie Song, Xiaomei Wang, Yulong Gao, Hongyu Cui

Journal: Int J Antimicrob Agents

PubMed ID: 37758064

Doi: 10.1016/j.ijantimicag.2023.106969

Products & Services: Proteins, Expression, Isolation and Analysis

Loss of function of FIGNL1, a DNA damage response gene, causes human ovarian dysgenesis

Authors: Natan Florsheim, Larisa Naugolni, Fouad Zahdeh, Orit Lobel, Batel Terespolsky, Rachel Michaelson-Cohen, Merav Y Gold, Michal Goldberg, Paul Renbaum, Ephrat Levy-Lahad, David Zangen

Journal: Eur J Endocrinol

PubMed ID: 37740949

Doi: 10.1093/ejendo/lvad127

Products & Services: Proteins, Expression, Isolation and Analysis

Acute and Long-Term Consequences of Co-opted doublesex on the Development of Mimetic Butterfly Color Patterns

Authors: Nicholas W VanKuren, Meredith M Doellman, Sofia I Sheikh, Daniela H Palmer Droguett, Darli Massardo, Marcus R Kronforst

Journal: Mol Biol Evol

PubMed ID: 37668300

Doi: 10.1093/molbev/msad196

Products & Services: Proteins, Expression, Isolation and Analysis

Is the co-option of jasmonate signalling for botanical carnivory universal trait for all carnivorous plants?

Authors: Andrej Pavlovič, Jana Koller, Ondřej Vrobel, Ivo Chamrád, René Lenobel, Peter Tarkowski