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CD70-specific CAR NK cells expressing IL-15 for the treatment of CD19-negative B-cell malignancy
Authors: Shanshan Guo, Wen Lei, Xueli Jin, Hui Liu, James Q Wang, Wenhai Deng, Wenbin Qian
Journal: Blood Adv
PubMed ID: 38564778
Doi: 10.1182/bloodadvances.2023012202
Products & Services: Codon Optimization   
Metagenomic exploration of cold-active enzymes for detergent applications: Characterization of a novel, cold-active and alkali-stable GH8 endoglucanase from ikaite columns in SW Greenland
Authors: Bianca Oliva, Athanasios Zervas, Peter Stougaard, Peter Westh, Mariane Schmidt Thøgersen
Journal: Microb Biotechnol
PubMed ID: 38829370
Doi: 10.1111/1751-7915.14466
Products & Services: Gene Synthesis   
Comparative Analysis of Orthosteric and Allosteric GLP-1R Agonists' Effects on Insulin Secretion from Healthy, Diabetic, and Recovered INS-1E Pancreatic Beta Cells
Authors: Joshua Reed, Victoria Higginbotham, Stephen Bain, Venkateswarlu Kanamarlapudi
Journal: Int J Mol Sci
PubMed ID: 38928038
Doi: 10.3390/ijms25126331
Products & Services: Catalog Peptides   
Molecular and structural basis of an ATPase-nuclease dual-enzyme anti-phage defense complex
Authors: Qiyin An, Yong Wang, Zhenhua Tian, Jie Han, Jinyue Li, Fumeng Liao, Feiyang Yu, Haiyan Zhao, Yancheng Wen, Heng Zhang & Zengqin Deng
Journal: Cell Research
PubMed ID: 38834762
Doi: 10.1038/s41422-024-00981-w
XIST dampens X chromosome activity in a SPEN-dependent manner during early human development
Authors: Charbel Alfeghaly, Gaël Castel, Emmanuel Cazottes, Madeleine Moscatelli, Eva Moinard, Miguel Casanova, Juliette Boni, Kasturi Mahadik, Jenna Lammers, Thomas Freour, Louis Chauviere, Carla Piqueras, Ruben Boers, Joachim Boers, Joost Gribnau, Laurent David, Jean-François Ouimette & Claire Rougeulle
Journal: Nat Struct Mol Biol
PubMed ID: 38834912
Doi: 10.1038/s41594-024-01325-3
Products & Services: Custom DNA/RNA Oligos   
Characterization and regulation of cell cycle-independent noncanonical gene targeting
Authors: Shinta Saito & Noritaka Adachi
Journal: Nature Communications
PubMed ID: 38890315
Doi: 10.1038/s41467-024-49385-9.
Products & Services: Gene Synthesis   
Protein engineering enables a soakable crystal form of human CDK7 primed for high-throughput crystallography and structure-based drug design
Authors: Manjeet Mukherjee, Philip J Day, Duncan Laverty, Juan A Bueren-Calabuig, Andrew J Woodhead, Charlotte Griffiths-Jones, Steve Hiscock, Charlotte East, Susan Boyd, Marc O'Reilly
Journal: Structure
PubMed ID: 38870939
Doi: 10.1016/j.str.2024.05.011
Products & Services: Custom Vector Construction   
Dual-Omics Approach Unveils Novel Perspective on the Quality Control of Genetically Engineered Exosomes
Authors: Christopher Olson, Konstantin Ivanov, Darin Boyes, David Bengford, Joy Ku, Renceh Flojo, Pengyang Zhang, Biao Lu
Journal: Pharmaceutics
PubMed ID: 38931944
Doi: 10.3390/pharmaceutics16060824
Products & Services: Molecular Biology Reagents   
Integrated pathway mining and selection of an artificial CYP79-mediated bypass to improve benzylisoquinoline alkaloid biosynthesis
Authors: Musashi Takenaka, Kouhei Kamasaka, Kim Daryong, Keiko Tsuchikane, Seiha Miyazawa, Saeko Fujihana, Yoshimi Hori, Christopher J Vavricka, Akira Hosoyama, Hiroko Kawasaki, Tomokazu Shirai, Michihiro Araki, Akira Nakagawa, Hiromichi Minami, Akihiko Kondo, Tomohisa Hasunuma
Journal: Microb Cell Fact
PubMed ID: 38879464
Doi: 10.1186/s12934-024-02453-7
Products & Services: Gene Synthesis   
Designing monomeric IFNγ: the significance of domain-swapped dimer structure in IFNγ immune responses
Authors: Yota Goto, Takamitsu Miyafusa, Shinya Honda
Journal: J Biol Chem
PubMed ID: 38879015
Doi: 10.1016/j.jbc.2024.107464
Products & Services: Molecular Biology Reagents   

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