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Constitutive activation mechanism of a class C GPCR
Authors: Jinwoo Shin, Junhyeon Park, Jieun Jeong, Jordy Homing Lam, Xingyu Qiu, Di Wu, Kuglae Kim, Joo-Youn Lee, Carol V Robinson, Jaekyung Hyun, Vsevolod Katritch, Kwang Pyo Kim, Yunje Cho
Journal: Nat Struct Mol Biol
PubMed ID: 38332368
Doi: 10.1038/s41594-024-01224-7
Design, quality and validation of the EU-OPENSCREEN fragment library poised to a high-throughput screening collection
Authors: Xavier Jalencas, Hannes Berg, Ludvik Olai Espeland, Sridhar Sreeramulu, Franziska Kinnen, Christian Richter, Charis Georgiou, Vladyslav Yadrykhinsky, Edgar Specker, Kristaps Jaudzems, Tanja Miletić, Robert Harmel, Phil Gribbon, Harald Schwalbe, Ruth Brenk, Aigars Jirgensons, Andrea Zaliani, Jordi Mestres
Journal: RSC Med Chem
PubMed ID: 38665834
Doi: 10.1039/d3md00724c
Cystatin from the helminth upregulates mevalonate and cholesterol biosynthesis pathways and immunomodulatory genes in human monocyte-derived dendritic cells
Authors: Nathalie Acevedo, Ana Lozano, Josefina Zakzuk, Kevin Llinás-Caballero, David Brodin, Peter Nejsum, Andrew R Williams, Luis Caraballo
Journal: Front Immunol
PubMed ID: 38481989
Doi: 10.3389/fimmu.2024.1328401
Products & Services: Molecular Biology Reagents   
Corrigendum: Enhanced immunogenicity and protective efficacy in mice following a Zika DNA vaccine designed by modulation of membrane-anchoring regions and its association to adjuvants
Authors: Franciane Mouradian Emidio Teixeira, Luana de Mendonça Oliveira, Anna Cláudia Calvielli Castelo Branco, Ricardo Wesley Alberca, Emanuella Sarmento Alho de Sousa, Bruno Henrique de Sousa Leite, Wenny Camilla Dos Santos Adan, Alberto José da Silva Duarte, Roberto Dias Lins, Maria Notomi Sato, Isabelle Freire Tabosa Viana
Journal: Front Immunol
PubMed ID: 38361947
Doi: 10.3389/fimmu.2024.1376059
UPP1 promotes lung adenocarcinoma progression through the induction of an immunosuppressive microenvironment
Authors: Yin Li, Manling Jiang, Ling Aye, Li Luo, Yong Zhang, Fengkai Xu, Yongqi Wei, Dan Peng, Xiang He, Jie Gu, Xiaofang Yu, Guoping Li, Di Ge, Chunlai Lu
Journal: Nat Commun .
PubMed ID: 38331898
Doi: 10.1038/s41467-024-45340-w
Cepharanthine analogs mining and genomes of Stephania accelerate anti-coronavirus drug discovery
Authors: Liang Leng, Zhichao Xu, Bixia Hong, Binbin Zhao, Ya Tian, Can Wang, Lulu Yang, Zhongmei Zou, Lingyu Li, Ke Liu, Wanjun Peng, Jiangning Liu, Zhoujie An, Yalin Wang, Baozhong Duan, Zhigang Hu, Chuan Zheng, Sanyin Zhang, Xiaodong Li, Maochen Li, Zhaoyu Liu, Zenghao Bi, Tianxing He, Baimei Liu, Huahao Fan, Chi Song, Yigang Tong, Shilin Chen
Journal: Nat Commun .
PubMed ID: 38378731
Doi: 10.1038/s41467-024-45690-5
Products & Services: Catalog Antibody   
Insertion of a FLAG-tag sequence at the end of exon 9 of the TBX5 gene in three induced pluripotent stem cell lines (DHMi004-A-4, DHMi004-A-5, DHMi004-A-6) by CRISPR/Cas9 technology
Authors: Harald Lahm, Niraj K Singh, Irina Gottmann, Stefanie A Doppler, Elda Dzilic, Heike Preisler, Stephanie Schneider, Rüdiger Lange, Markus Krane, Martina Dreßen
Journal: Cell Research
PubMed ID: 38100916
Doi: 10.1016/j.scr.2023.103261
Products & Services: Plasmid DNA Preparation   
Carotenoid cleavage enzymes evolved convergently to generate the visual chromophore
Authors: Yasmeen J Solano , Michael P Everett , Kelly S Dang , Jude Abueg , Philip D Kiser
Journal: Nature Chemical Biology
PubMed ID: 38355721
Doi: 10.1038/s41589-024-01554-z
Products & Services: Plasmid DNA Preparation   
Unraveling the Catalytic Mechanism of Taxadiene-5α-hydroxylase from Crystallography and Computational Analyses
Authors: Xitong Song, Qian Wang, Xiaoxi Zhu, Wenhan Fang, Xiaonan Liu, Chao Shi, Zhenzhan Chang, Huifeng Jiang, and Binju Wang
Journal: ACS Catal
Doi: doi.org/10.1021/acscatal.3c05807
Products & Services: Gene Synthesis   
Neuroprotective effects of annexin A1 tripeptide in rats with sepsis-associated encephalopathy
Authors: Qiao Cui, Nannan Qin, Yonghan Zhang, Yanmei Miao, Leiyu Xie, Xinglong Ma, Zhiquan Zhang, Peng Xie
Journal: Biotechnol Appl Biochem
PubMed ID: 38409880
Doi: 10.1002/bab.2569
Products & Services: Peptide Synthesis   

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