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Controlled TPCA-1 delivery engineers a pro-tenogenic niche to initiate tendon regeneration by targeting IKKβ/NF-κB signaling

Authors: Jialin Chen , Renwang Sheng , Qingyun Mo , Ludvig J Backman , Zhiyuan Lu , Qiuzi Long , Zhixuan Chen , Zhicheng Cao , Yanan Zhang , Chuanquan Liu , Haotian Zheng , Yu Qi , Mumin Cao , Yunfeng Rui , Wei Zhang

Journal: Bioact Mater

PubMed ID: 39512422

Doi: 10.1016/j.bioactmat.2024.10.016

Products & Services: Recombinant Proteins

Bitter taste receptor TAS2R14 activation and G protein assembly by an intracellular agonist

Authors: Lele Tao , Dongxue Wang , Qingning Yuan Fenghui Zhao , Yu Zhang , Tianyuan Du , Shiyi Shen , H Eric Xu , Yi Li , Dehua Yang , Jia Duan

Journal: Cell Research

PubMed ID: 38969802

Doi: 10.1038/s41422-024-00995-4

Products & Services: Catalog Peptides

Retrograde transport of neurotrophin receptor TrkB-FL induced by excitotoxicity regulates Golgi stability and is a target for stroke neuroprotection

Authors: Gema María Esteban-Ortega, Margarita Díaz-Guerra

Journal: bioRxiv

Doi: doi.org/10.1101/2024.10.29.620835

Products & Services: Peptide Synthesis Proteins, Expression, Isolation and Analysis

Mechanism of nucleosomal H2A K13/15 monoubiquitination and adjacent dual monoubiquitination by RNF168

Authors: Huasong Ai , Zebin Tong , Zhiheng Deng , Qiang Shi, Shixian Tao , Gaoge Sun, Jiawei Liang , Maoshen Sun , Xiangwei Wu , Qingyun Zheng , Lujun Liang , Hang Yin , Jia-Bin Li , Shuai Gao , Changlin Tian , Lei Liu , Man Pan

Journal: Nature Chemical Biology

PubMed ID: 39394267

Doi: doi.org/10.1038/s41589-024-01750-x

Products & Services: Gene Synthesis PCR and Cloning

Natural SNP Variation in GbOSM1 Promotor Enhances Verticillium Wilt Resistance in Cotton

Authors: Guilin Wang, Dayong Zhang , Haitang Wang , Jinmin Kong , Zhiguo Chen , Chaofeng Ruan , Chaoyang Deng , Qihang Zheng , Zhan Guo , Hanqiao Liu, Weixi Li , Xinyu Wang , Wangzhen Guo

Journal: Advanced Science

PubMed ID: 39413014

Doi: 10.1002/advs.202406522

Products & Services: Proteins, Expression, Isolation and Analysis

4-aminopyridine attenuates inflammation and apoptosis and increases angiogenesis to promote skin regeneration following a burn injury in mice

Authors: Rahul V G , Govindaraj Ellur , Amir A Gaber , Prem Kumar Govindappa , John C Elfar

Journal: Cell Death Discov

PubMed ID: 39366954

Doi: 10.1038/s41420-024-02199-6

Products & Services: Proteins, Expression, Isolation and Analysis

SOX4 facilitates brown fat development and maintenance through EBF2-mediated thermogenic gene program in mice

Authors: Shuai Wang, Ting He, Ya Luo, Kexin Ren, Huanming Shen, Lingfeng Hou, Yixin Wei, Tong Fu, Wenlong Xie, Peng Wang, Jie Hu, Yu Zhu, Zhengrong Huang, Qiyuan Li, Weihua Li, Huiling Guo & Boan Li

Journal: Cell death and differentiation

PubMed ID: 39402212

Products & Services: Catalog Antibody

Orientia tsutsugamushi Ank5 promotes NLRC5 cytoplasmic retention and degradation to inhibit MHC class I expression

Authors: Haley E Adcox , Jason R Hunt , Paige E Allen , Thomas E Siff , Kyle G Rodino , Andrew K Ottens , Jason A Carlyon

Journal: Nature Communications

PubMed ID: 39277599

Doi: 10.1038/s41467-024-52119-6

Products & Services: Custom Vector Construction Codon Optimization

Efficient circularization of protein-encoding RNAs via a novel cis-splicing system

Authors: Shaojun Qi , Huiming Wang , Guopeng Liu , Qianshan Qin , Peng Gao , Bo Ying

Journal: Nucleic Acids Research