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ECSIT facilitates memory CD8+ T cell development by mediating fumarate synthesis during viral infection and tumorigenesis

Authors: Yongbing Yang , Yanan Wang , Zhongcheng Wang , Huanyu Yan , Yi Gong , Yingchao Hu , Yuying Jiang , Shuang Wen , Feifei Xu , Bingwei Wang , Fiachra Humphries , Yun Chen , Xi Wang , Shuo Yang

Journal: Nat Cell Biol .

PubMed ID: 38326554

Doi: 10.1038/s41556-024-01351-9

Products & Services: Peptide Synthesis

Unveiling the structural mechanisms of nonpeptide ligand recognition and activation in human chemokine receptor CCR8

Authors: Shan Jiang , Xi Lin , Lijie Wu , Ling Wang , Yiran Wu , Ziyi Xu , Fei Xu

Journal: Sci Adv .

PubMed ID: 38306437

Doi: 10.1126/sciadv.adj7500

Products & Services: Codon Optimization

Integrating network pharmacology and experimental models to identify notoginsenoside R1 ameliorates atherosclerosis by inhibiting macrophage NLRP3 inflammasome activation

Authors: Jingyue Yu, Jinyu Hu, Margaret Baldini, Huan Lei, Lei Li, Shanshan Luo, Jielian Wu, Xupin Liu, Dan Shan, Yanfei Xie, Haihong Fang, Jun Yu

Journal: J Nat Med

PubMed ID: 38409483

Doi: 10.1007/s11418-023-01776-w

Products & Services: PCR Cloning and Subcloning

Membrane-Associated Ubiquitin Ligase RING Finger Protein 152 Orchestrates Melanogenesis via Tyrosinase Ubiquitination

Authors: Ryota Ueda, Rina Hashimoto, Yuki Fujii, José C J M D S Menezes, Hirotaka Takahashi, Hiroyuki Takeda, Tatsuya Sawasaki, Tomonori Motokawa, Kenzo Tokunaga, Hideaki Fujita

Journal: Membranes (Basel)

PubMed ID: 38392670

Doi: 10.3390/membranes14020043

Maternal Phlorizin Intake Protects Offspring from Maternal Obesity-Induced Metabolic Disorders in Mice via Targeting Gut Microbiota to Activate the SCFA-GPR43 Pathway

Authors: Xueran Mei, Yi Li, Xiaoyu Zhang, Xiwen Zhai, Yi Yang, Zhengjuan Li, Liping Li

Journal: J Agric Food Chem

PubMed ID: 38349207

Doi: 10.1021/acs.jafc.3c06370

Products & Services: Proteins, Expression, Isolation and Analysis

Targeting deoxynivalenol for degradation by a chimeric manganese peroxidase/glutathione system

Authors: Xiaoyun Su, Shuai Wang, Xiaolu Wang, Wangli Ji, Honglian Zhang, Tao Tu, Nina Hakulinen, Huiying Luo, Wei Zhang, Huoqing Huang

Journal: Ecotoxicol Environ Saf