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Predicting multiple conformations via sequence clustering and AlphaFold2

Authors: Hannah K Wayment-Steele, Adedolapo Ojoawo, Renee Otten, Julia M Apitz, Warintra Pitsawong, Marc Hömberger, Sergey Ovchinnikov, Lucy Colwell, Dorothee Kern

Journal: Nature

PubMed ID: 37956700

Doi: 10.1038/s41586-023-06832-9

Products & Services: Custom Vector Construction

A new antibiotic traps lipopolysaccharide in its intermembrane transporter

Authors: Karanbir S Pahil, Morgan S A Gilman, Vadim Baidin, Thomas Clairfeuille, Patrizio Mattei, Christoph Bieniossek, Fabian Dey, Dieter Muri, Remo Baettig, Michael Lobritz, Kenneth Bradley, Andrew C Kruse 4, Daniel Kahne 5

Journal: Nature

PubMed ID: 38172635

Doi: 10.1038/s41586-023-06799-7

Products & Services: Peptide Synthesis

Computationally designed sensors detect endogenous Ras activity and signaling effectors at subcellular resolution

Authors: Jason Z. Zhang, William H. Nguyen, Nathan Greenwood, John C. Rose, Shao-En Ong, Dustin J. Maly & David Baker

Journal: Nature Biotechnol

PubMed ID: 38228150

Doi: 10.1038/s41587-023-02107-w

Products & Services: Plasmid DNA Preparation

Microglia-derived exosomes modulate myelin regeneration via miR-615-5p/MYRF axis

Authors: Xiao-Yu Ji, Yu-Xin Guo, Li-Bin Wang, Wen-Cheng Wu, Jia-Qi Wang, Jin He, Rui Gao, Javad Rasouli, Meng-Yuan Gao, Zhen-Hai Wang, Dan Xiao, Wei-Feng Zhang, Bogoljub Ciric, Yuan Zhang, Xing Li

Journal: J Neuroinflammation

PubMed ID: 38246987

Doi: 10.1186/s12974-024-03019-5

Products & Services: Catalog Peptides

A CRISPR-Cas12a-based electrochemical biosensor for the detection of microphthalmia-associated transcription factor

Authors: Qisheng Luo, Chunyuan Zhang, Xiandong Deng, Dongyuan Liu, Xingchen Pan, Yuanxun Gong, Qianli Tang, Kai Zhang, Xianjiu Liao

Journal: Mikrochim Acta

PubMed ID: 38170285

Doi: 10.1007/s00604-023-06164-5

Products & Services: Custom DNA/RNA Oligos

Fragment-based screening targeting an open form of the SARS-CoV-2 main protease binding pocket

Authors: Chia Ying Huang, Alexander Metz, Roland Lange, Nadia Artico, Céline Potot, Julien Hazemann, Manon Müller, Marina Dos Santos, Alain Chambovey, Daniel Ritz, Deniz Eris, Solange Meyer, Geoffroy Bourquin, May Sharpe, Aengus Mac Sweeney

Journal: Acta Crystallogr D Struct Biol

PubMed ID: 38289714

Doi: 10.1107/S2059798324000329

Products & Services: Proteins, Expression, Isolation and Analysis

Beta-1,3-Glucan-Binding Protein Inhibits Dengue and ZIKA Virus Replication

Authors: Xiaoxue Xie, Di Wang, Bo Li, Guorui Liang, Xiaoli Chen, Dan Xing, Teng Zhao, Xinyu Zhou, Chunxiao Li

Journal: Biomedicines

PubMed ID: 38255195

Doi: 10.3390/biomedicines12010088

Products & Services: DNA Sequencing

S100A12 protein as a porcine health status biomarker when quantified in saliva samples

Authors: A M Gutiérrez, M Matas-Quintanilla, M Piñeiro, J Sánchez, P Fuentes, F J Ibáñez-López