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Neutrophil-mediated type IV collagen degradation is elevated in patients with mild endoscopic ulcerative colitis reflecting early mucosal destruction
Authors: Marta S Alexdottir, Martin Pehrsson, Viktor Domislovic, Line E Godskesen, Aleksander Krag, Jens Kjeldsen, Marko Brinar, Ana Barisic, Anne-Christine Bay-Jensen, Morten A Karsdal, Zeljko Krznaric, Joachim H Mortensen
Journal: Sci Rep
PubMed ID: 38238446
Doi: 10.1038/s41598-024-52208-y
Products & Services: Catalog Peptides   
TXNRD1 drives the innate immune response in senescent cells with implications for age-associated inflammation
Authors: Xue Hao, Bo Zhao, Martina Towers, Liping Liao, Edgar Luzete Monteiro, Xin Xu, Christina Freeman, Hongzhuang Peng, Hsin-Yao Tang, Aaron Havas, Andrew V Kossenkov, Shelley L Berger, Peter D Adams, David W Speicher, David Schultz, Ronen Marmorstein, Kenneth S Zaret, Rugang Zhang
Journal: Nat Aging
PubMed ID: 38267705
Doi: 10.1038/s43587-023-00564-1
Products & Services: Mutant Libraries   
LUBAC-mediated M1 Ub regulates necroptosis by segregating the cellular distribution of active MLKL
Authors: Nadine Weinelt, Kaja Nicole Wächtershäuser, Gulustan Celik, Birte Jeiler, Isabelle Gollin, Laura Zein, Sonja Smith, Geoffroy Andrieux, Tonmoy Das, Jens Roedig, Leonard Feist, Björn Rotter, Melanie Boerries, Francesco Pampaloni, Sjoerd J L van Wijk
Journal: Cell Death Dis
PubMed ID: 38245534
Doi: 10.1038/s41419-024-06447-6
Combined Immunoinformatics to Design and Evaluate a Multi-Epitope Vaccine Candidate against Infection
Authors: Song Liang, Shidan Zhang, Yinli Bao, Yumin Zhang, Xinyi Liu, Huochun Yao, Guangjin Liu
Journal: Vaccines (Basel)
PubMed ID: 38400121
Doi: 10.3390/vaccines12020137
Products & Services: Catalog Antibody   
Extended Cleavage Specificity of two Hematopoietic Serine Proteases from a Ray-Finned Fish, the Spotted Gar ()
Authors: Paolo Valentini, Srinivas Akula, Abigail Alvarado-Vazquez, Jenny Hallgren, Zhirong Fu, Brett Racicot, Ingo Braasch, Michael Thorpe, Lars Hellman
Journal: Int J Mol Sci
PubMed ID: 38338947
Doi: 10.3390/ijms25031669
Products & Services: Molecular Biology Reagents   
USP50 suppresses alternative RecQ helicase use and deleterious DNA2 activity during replication
Authors: Hannah L Mackay, Helen R Stone, Katherine Ellis, George E Ronson, Alexandra K Walker, Katarzyna Starowicz, Alexander J Garvin, Patrick van Eijk, Alina Vaitsiankova, Sobana Vijayendran, James F Beesley, Eva Petermann, Eric J Brown, Ruth M Densham, Simon H Reed, Felix Dobbs, Marco Saponaro, Joanna R Morris
Journal: biorxiv
PubMed ID: 38260523
Doi: 10.1101/2024.01.10.574674
Products & Services: Molecular Biology Reagents   
PARP1-DNA co-condensation drives DNA repair site assembly to prevent disjunction of broken DNA ends
Authors: Nagaraja Chappidi 1, Thomas Quail 2, Simon Doll 3, Laura T Vogel 4, Radoslav Aleksandrov 5, Suren Felekyan 4, Ralf Kühnemuth 4, Stoyno Stoynov 5, Claus A M Seidel 4, Jan Brugués 6, Marcus Jahnel 3, Titus M Franzmann 1, Simon Alberti
Journal: Cell
PubMed ID: 38320550
Doi: 10.1016/j.cell.2024.01.015
Products & Services: Codon Optimization   Gene Synthesis   
PARP1 condensates differentially partition DNA repair proteins and enhance DNA ligation
Authors: Christopher Chin Sang, Gaelen Moore, Maria Tereshchenko, Michael L Nosella, Hongshan Zhang, T Reid Alderson, Morgan Dasovich, Anthony Leung, Ilya J Finkelstein, Julie D Forman-Kay, Hyun O Lee
Journal: biorxiv
PubMed ID: 38328070
Doi: 10.1101/2024.01.20.575817
Products & Services: Gene Synthesis   
CFL1 restores the migratory capacity of bone marrow mesenchymal stem cells in primary Sjögren's syndrome by regulating CCR1 expression
Authors: Mengxi Huang, Panpan Zhou, Yang Hang, Dan Wu, Nan Zhao, Genhong Yao, Xiaojun Tang, Lingyun Sun
Journal: Int Immunopharmacol
PubMed ID: 38183912
Doi: 10.1016/j.intimp.2024.111485
Products & Services: Molecular Biology Reagents   
A novel opsonic eCIRP inhibitor for lethal sepsis
Authors: Colleen P Nofi, Chuyi Tan, Gaifeng Ma, Molly Kobritz, Jose M Prince, Haichao Wang, Monowar Aziz, Ping Wang
Journal: J Leukoc Biol
PubMed ID: 37774691
Doi: 10.1093/jleuko/qiad119
Products & Services: Catalog Peptides   

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