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Development of a highly efficient prime editor system in mice and rabbits
Authors: Yuqiang Qian , Di Wang , Wenchao Niu , Zheng Shi , Mao Wu , Ding Zhao , Jinze Li , Xun Gao , Zhongtian Zhang , Liangxue Lai , Zhanjun Li
Journal: Cell Mol Life Sci .
PubMed ID: 37924393
Doi: 10.1007/s00018-023-05003-3
Products & Services: Synthetic sgRNA and crRNA Service   
Interactions of Histone Deacetylase 6 with DNA Damage Repair Factors Strengthen its Utility as a Combination Drug Target in High-Grade Serous Ovarian Cancer
Authors: Jolene M Duda, Stefani N Thomas
Journal: ACS Pharmacol Transl Sci
PubMed ID: 38107255
Doi: 10.1021/acsptsci.3c00215
Products & Services: Proteins, Expression, Isolation and Analysis   
Critical role of TPRN rings in the stereocilia for hearing
Authors: Jieyu Qi, Fangzhi Tan, Liyan Zhang, Yinyi Zhou, Ziyu Zhang, Qiuhan Sun, Nianci Li, Yuan Fang, Xin Chen, Yunhao Wu, Guisheng Zhong, Renjie Chai
Journal: Mol Ther
PubMed ID: 37952086
Doi: 10.1016/j.ymthe.2023.11.011
Products & Services: Proteins, Expression, Isolation and Analysis   
DNAJB6 mutants display toxic gain of function through unregulated interaction with Hsp70 chaperones
Authors: Meital Abayev-Avraham, Yehuda Salzberg, Dar Gliksberg, Meital Oren-Suissa, Rina Rosenzweig
Journal: Nat Commun
PubMed ID: 37923706
Doi: 10.1038/s41467-023-42735-z
Products & Services: Proteins, Expression, Isolation and Analysis   
A role for cytoglobin in regulating intracellular hydrogen peroxide and redox signals in the vasculature
Authors: Clinton Mathai, Frances Jourd'heuil, Le Gia Cat Pham, Kurrim Gilliard, Joseph Balnis, Annie Jen, Katherine A Overmyer, Joshua J Coon, Ariel Jaitovich, Benoit Boivin, David Jourd'heuil
Journal: biorxiv
PubMed ID: 37034694
Doi: 10.1101/2023.03.31.535146
Products & Services: Proteins, Expression, Isolation and Analysis   
Regulated secretion of mutant p53 negatively affects T lymphocytes in the tumor microenvironment
Authors: Xiang Dong, Chunlu Li, Chengsi Deng, Jingwei Liu, Danni Li, Tingting Zhou, Xindi Yang, Yunchan Liu, Qiqiang Guo, Yanling Feng, Yang Yu, Zhuo Wang, Wendong Guo, Siyi Zhang, Hongyan Cui, Cui Jiang, Xiwen Wang, Xiaoyu Song, Xun Sun, Liu Cao
Journal: Oncogene
PubMed ID: 37952080
Doi: 10.1038/s41388-023-02886-1
Products & Services: Proteins, Expression, Isolation and Analysis   
A novel ultrasensitive assay for plasma p-tau217: Performance in individuals with subjective cognitive decline and early Alzheimer's disease
Authors: Fernando Gonzalez-Ortiz, Pamela C L Ferreira, Armand González-Escalante, Laia Montoliu-Gaya, Paula Ortiz-Romero, Przemyslaw R Kac, Michael Turton, Hlin Kvartsberg, Nicholas J Ashton, Henrik Zetterberg, Peter Harrison, Bruna Bellaver, Guilherme Povala, Victor L Villemagne, Tharick A Pascoal, Mary Ganguli, Anne D Cohen, Carolina Minguillon, Jose Contador, Marc Suárez-Calvet, Thomas K Karikari, Kaj Blennow
Journal: Alzheimers Dement
PubMed ID: 37975513
Doi: 10.1002/alz.13525
Plant carbonic anhydrase-like enzymes in neuroactive alkaloid biosynthesis
Authors: Ryan S Nett, Yaereen Dho, Chun Tsai, Daria Passow, Jaime Martinez Grundman, Yun-Yee Low, Elizabeth S Sattely
Journal: Nature
PubMed ID: 37938780
Doi: 10.1038/s41586-023-06716-y
Products & Services: Proteins, Expression, Isolation and Analysis   
Unlocking the potential of allogeneic Vδ2 T cells for ovarian cancer therapy through CD16 biomarker selection and CAR/IL-15 engineering
Authors: Derek Lee, Zachary Spencer Dunn, Wenbin Guo, Carl J Rosenthal, Natalie E Penn, Yanqi Yu, Kuangyi Zhou, Zhe Li, Feiyang Ma, Miao Li, Tsun-Ching Song, Xinjian Cen, Yan-Ruide Li, Jin J Zhou, Matteo Pellegrini, Pin Wang, Lili Yang
Journal: Nat Commun
PubMed ID: 37938576
Doi: 10.1038/s41467-023-42619-2
Products & Services: Synthetic sgRNA and crRNA Service   
Phages overcome bacterial immunity via diverse anti-defence proteins
Authors: Erez Yirmiya, Azita Leavitt, Allen Lu, Adelyn E Ragucci, Carmel Avraham, Ilya Osterman, Jeremy Garb, Sadie P Antine, Sarah E Mooney, Samuel J Hobbs, Philip J Kranzusch, Gil Amitai, Rotem Sorek
Journal: Nature
PubMed ID: 37992756
Doi: 10.1038/s41586-023-06869-w
Products & Services: Gene Synthesis   

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