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Protein engineering enables a soakable crystal form of human CDK7 primed for high-throughput crystallography and structure-based drug design
Authors: Manjeet Mukherjee, Philip J Day, Duncan Laverty, Juan A Bueren-Calabuig, Andrew J Woodhead, Charlotte Griffiths-Jones, Steve Hiscock, Charlotte East, Susan Boyd, Marc O'Reilly
Journal: Structure
PubMed ID: 38870939
Doi: 10.1016/j.str.2024.05.011
Products & Services: Custom Vector Construction   
The BICD2 dynein cargo adaptor binds to the HPV16 L2 capsid protein and promotes HPV infection
Authors: Kaitlyn Speckhart, Jeongjoon Choi, Daniel DiMaio, Billy Tsai
Journal: PLoS Pathog
PubMed ID: 38829892
Doi: 10.1371/journal.ppat.1012289
Products & Services: Catalog Peptides   
The role of shear forces in primary and secondary nucleation of amyloid fibrils
Authors: Emil Axell, Jing Hu, Max Lindberg, Alexander J Dear, Lei Ortigosa-Pascual, Ewa A Andrzejewska, Greta Šneiderienė, Dev Thacker, Tuomas P J Knowles, Emma Sparr, Sara Linse
Journal: Proc Natl Acad Sci U S A
PubMed ID: 38875148
Doi: 10.1073/pnas.2322572121
Products & Services: Molecular Biology Reagents   
Dual-Omics Approach Unveils Novel Perspective on the Quality Control of Genetically Engineered Exosomes
Authors: Christopher Olson, Konstantin Ivanov, Darin Boyes, David Bengford, Joy Ku, Renceh Flojo, Pengyang Zhang, Biao Lu
Journal: Pharmaceutics
PubMed ID: 38931944
Doi: 10.3390/pharmaceutics16060824
Products & Services: Molecular Biology Reagents   
The generation of stable transgenic lines in the human-infective nematode Strongyloides stercoralis
Authors: Ruhi Patel, Astra S Bryant, Michelle L Castelletto, Breanna Walsh, Damia Akimori, Elissa A Hallem
Journal: G3 (Bethesda)
PubMed ID: 38839055
Doi: 10.1093/g3journal/jkae122
Products & Services: Molecular Biology Reagents   
The annotation of has been concealed by its protein-coding pseudogene
Authors: Emil K Gustavsson, Siddharth Sethi, Yujing Gao, Jonathan W Brenton, Sonia García-Ruiz, David Zhang, Raquel Garza, Regina H Reynolds, James R Evans, Zhongbo Chen, Melissa Grant-Peters, Hannah Macpherson, Kylie Montgomery, Rhys Dore, Anna I Wernick, Charles Arber, Selina Wray, Sonia Gandhi, Julian Esselborn, Cornelis Blauwendraat, Christopher H Douse, Anita Adami, Diahann A M Atacho, Antonina Kouli, Annelies Quaegebeur, Roger A Barker, Elisabet Englund, Frances Platt, Johan Jakobsson, Nicholas W Wood, Henry Houlden, Harpreet Saini, Carla F Bento, John Hardy, Mina Ryten
Journal: Sci Adv
PubMed ID: 38924406
Doi: 10.1126/sciadv.adk1296
Arabidopsis pollen prolyl-hydroxylases P4H4/6 are relevant for correct hydroxylation and secretion of LRX11 in pollen tubes
Authors: Ana R Sede, Diego L Wengier, Cecilia Borassi, Martiniano Ricardi, Sofía C Somoza, Rafael Aguiló, José M Estevez, Jorge P Muschietti
Journal: J Exp Bot
PubMed ID: 38877792
Doi: 10.1093/jxb/erae269
Ancient nitrogenases are ATP dependent
Authors: Derek F Harris, Holly R Rucker, Amanda K Garcia, Zhi-Yong Yang, Scott D Chang, Hannah Feinsilber, Betül Kaçar, Lance C Seefeldt
Journal: MBio
PubMed ID: 38869277
Doi: 10.1128/mbio.01271-24
MiR-23b-3p alleviates Sjögren's syndrome by targeting SOX6 and inhibiting the NF-κB signaling
Authors: Yan Cai, Yi Zhang, Sihan Wang, E Changyong
Journal: Mol Immunol
PubMed ID: 38901181
Doi: 10.1016/j.molimm.2024.06.002
Products & Services: Gene Synthesis   
PDZ2-conjugated-PLGA nanoparticles are tiny heroes in the battle against SARS-CoV-2
Authors: Noah Giacon, Ettore Lo Cascio, Valeria Pennacchietti, Flavio De Maio, Giulia Santarelli, Diego Sibilia, Federica Tiberio, Maurizio Sanguinetti, Wanda Lattanzi, Angelo Toto, Alessandro Arcovito
Journal: Sci Rep
PubMed ID: 38844490
Doi: 10.1038/s41598-024-63239-w
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