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Macrophage SUCLA2 coupled glutaminolysis manipulates obesity through AMPK

Authors: Chang Peng, Haowen Jiang, Liya Jing, Wenhua Yang, Xiaotong Guan, Hanlin Wang, Sike Yu, Yutang Cao, Min Wang, Huan Ma, Zan Lv, Hongyu Gu, Chunmei Xia, Xiaozhen Guo, Bin Sun, Aili Wang, Cen Xie, Wenbiao Wu, Luyiyi Lu, Jiayi Song, Saifei Lei, Rui Wu, Yi Zang, Erjiang Tang, Jia Li

Journal: Nat Commun

PubMed ID: 39966410

Doi: 10.1038/s41467-025-57044-w

Products & Services: Peptide Synthesis

PSKH1 kinase activity is differentially modulated via allosteric binding of Ca2+ sensor proteins

Authors: Christopher R Horne, Toby A Dite, Samuel N Young, Lucy J Mather, Laura F Dagley, Jared L Johnson, Tomer M Yaron-Barir, Emily M Huntsman, Leonard A Daly, Dominic P Byrne, Antonia L Cadell, Boaz H Ng, Jumana Yousef, Dylan H Multari, Lianju Shen, Luke M McAloon, Gerard Manning, Mark A Febbraio, Anthony R Means, Lewis C Cantley, Maria C Tanzer, David R Croucher, Claire E Eyers, Patrick A Eyers, John W Scott, James M Murphy

Journal: Proc Natl Acad Sci U S A

PubMed ID: 39964718

Doi: 10.1073/pnas.2420961122

Products & Services: Peptide Synthesis

Enhancing mRNA translation efficiency by introducing sequence optimized AU-rich elements in 3′ UTR via HuR anchorage

Authors: Xinghuan Ma , Sujia Liu , Bangda Fan , Danni Jin , Lei Miao , Lin Liu , Shubo Du , Jiaqi Lin

Journal: Mol Ther Nucleic Acids

PubMed ID: 40125272

Doi: doi.org/10.1016/j.omtn.2025.102485

Products & Services: Gene Synthesis

Controllable intein splicing and N-terminal cleavage at mesophilic temperatures

Authors: Taylor A McNeal, Joel Weinberger, Geraldy L S Liman, Tia M Ariagno, David W Wood, Thomas J Santangelo, Christopher W Lennon