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Silmitasertib (CX-4945), a Clinically Used CK2-Kinase Inhibitor with Additional Effects on GSK3β and DYRK1A Kinases: A Structural Perspective
Authors: Przemyslaw Grygier, Katarzyna Pustelny, Jakub Nowak, Przemyslaw Golik, Grzegorz M Popowicz, Oliver Plettenburg, Grzegorz Dubin, Filipe Menezes, Anna Czarna
Journal: J Med Chem
PubMed ID: 36883902
Doi: 10.1021/acs.jmedchem.2c01887
Products & Services: Combinatorial DNA Libraries   
Cancer Cell Resistance to IFNγ Can Occur via Enhanced Double-Strand Break Repair Pathway Activity
Authors: Tong Han, Xujun Wang, Sailing Shi, Wubing Zhang, Jue Wang, Qiu Wu, Ziyi Li, Jingxin Fu, Rongbin Zheng, Jiamin Zhang, Qin Tang, Peng Zhang, Chenfei Wang
Journal: cancer immunology research
PubMed ID: 36629846
Doi: 10.1158/2326-6066.CIR-22-0056
Structural basis for motilin and erythromycin recognition by motilin receptor
Authors: Chongzhao You, Yumu Zhang, Youwei Xu, Peiyu Xu, Zhen Li, Huadong Li, Sijie Huang, Zecai Chen, Jingru Li, H Eric Xu, Yi Jiang
Journal: Science Advances
PubMed ID: 36921049
Doi: 10.1126/sciadv.ade9020
Products & Services: Peptide Synthesis   
Alphaherpesvirus upregulates NDRG1 expression to facilitate the nuclear import of viral UL31 and UL34 proteins
Authors: Shuang Zhang, Sheng-Li Ming, Lei Zeng, Lu-Fang Wang, Chao Zhang, He-Shui Zhu, Guo-Yu Yang, Gai-Ping Zhang, Bei-Bei Chu, Jiang Wang
Journal: J Med Virol
PubMed ID: 36807585
Doi: 10.1002/jmv.28591
Design and preclinical evaluation of a universal SARS-CoV-2 mRNA vaccine
Authors: Jane Qin, Ju Hyeong Jeon, Jiangsheng Xu, Laura Katherine Langston, Ramesh Marasini, Stephanie Mou, Brian Montoya, Carolina R Melo-Silva, Hyo Jin Jeon, Tianyi Zhu, Luis J Sigal, Renhuan Xu, Huabin Zhu
Journal: Front Immunol
PubMed ID: 37033973
Doi: 10.3389/fimmu.2023.1126392
Products & Services: Peptide Synthesis   
Entropy-driven assisted T7 RNA polymerase amplification-activated CRISPR/Cas13a activity for SARS-CoV-2 detection in human pharyngeal swabs and environment by an electrochemiluminescence biosensor
Authors: Jihua Wei, Zichun Song, Jiuying Cui, Yuanxun Gong, Qianli Tang, Kai Zhang, Xinlei Song, Xianjiu Liao
Journal: J Hazard Mater
PubMed ID: 36965355
Doi: 10.1016/j.jhazmat.2023.131268
Exploring the structural basis to develop efficient multi-epitope vaccines displaying interaction with HLA and TAP and TLR3 molecules to prevent NIPAH infection, a global threat to human health
Authors: Sukrit Srivastava, Sonia Verma, Mohit Kamthania, Ajay Kumar Saxena, Kailash C Pandey, Veena Pande, Michael Kolbe
Journal: PLoS ONE
PubMed ID: 36920996
Doi: 10.1371/journal.pone.0282580
A short-chain carbonyl reductase mutant is an efficient catalyst in the production of (R)-1,3-butanediol
Authors: Xiaoyan Guo, Yunfang Gao, Fangzheng Liu, Yong Tao, Haibo Jin, Jianjun Wang, Sheng Wu
Journal: Microb Biotechnol
PubMed ID: 36946330
Doi: 10.1111/1751-7915.14249
Products & Services: Molecular Biology Reagents   
Adenosine deaminase augments SARS-CoV-2 specific cellular and humoral responses in aged mouse models of immunization and challenge
Authors: Ebony N Gary, Nicholas J Tursi, Bryce M Warner, Gina Cuismano, Jennifer Connors, Elizabeth M Parzych, Bryan D Griffin, Matthew R Bell, Ali R Ali, Drew Frase, Casey E Hojecki, Gabriela A Canziani, Irwin Chaiken, Toshitha Kannan, Estella Moffat, Carissa Embury-Hyatt, Sarah K Wooton, Andrew Kossenkov, Ami Patel, Darwyn Kobasa, Michele A Kutzler, Elias K Haddad, David B Weiner
Journal: Front Immunol
PubMed ID: 36999023
Doi: 10.3389/fimmu.2023.1138609
Products & Services: Molecular Biology Reagents   
A chemically controlled Cas9 switch enables temporal modulation of diverse effectors
Authors: Cindy T Wei, Nicholas A Popp, Omri Peleg, Rachel L Powell, Elhanan Borenstein, Dustin J Maly, Douglas M Fowler
Journal: Nat Chem Biol
PubMed ID: 36879061
Doi: 10.1038/s41589-023-01278-6
Products & Services: Codon Optimization   

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