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CAR affinity modulates the sensitivity of CAR-T cells to PD-1/PD-L1-mediated inhibition
Authors: Irene Andreu-Saumell, Alba Rodriguez-Garcia, Vanessa Mühlgrabner, Marta Gimenez-Alejandre, Berta Marzal, Joan Castellsagué, Fara Brasó-Maristany, Hugo Calderon, Laura Angelats, Salut Colell, Mara Nuding, Marta Soria-Castellano, Paula Barbao, Aleix Prat, Alvaro Urbano-Ispizua, Johannes B Huppa, Sonia Guedan
Journal: Nat Commun
PubMed ID: 38670972
Doi: 10.1038/s41467-024-47799-z
Products & Services: Catalog Peptides   
An ultraviolet-driven rescue pathway for oxidative stress to eye lens protein human gamma-D crystallin
Authors: Jake A Hill, Yvonne Nyathi, Sam Horrell, David von Stetten, Danny Axford, Robin L Owen, Godfrey S Beddard, Arwen R Pearson, Helen M Ginn, Briony A Yorke
Journal: Commun Chem
PubMed ID: 38600176
Doi: 10.1038/s42004-024-01163-w
Products & Services: Mutant Libraries   
Online monitoring of protein refolding in inclusion body processing using intrinsic fluorescence
Authors: Chika Linda Igwe, Don Fabian Müller, Florian Gisperg, Jan Niklas Pauk, Matthias Kierein, Mohamed Elshazly, Robert Klausser, Julian Kopp, Oliver Spadiut, Eva Přáda Brichtová
Journal: Anal Bioanal Chem
PubMed ID: 38573344
Doi: 10.1007/s00216-024-05249-1
Products & Services: Codon Optimization   
Immunometric and functional measurement of endogenous vasoinhibin in human sera
Authors: Magdalena Zamora, David Harris, Nils Davies, Johannes Ebnet, Peter Radermacher, Cosima Brucker, Christiane Waller, Juan Pablo Robles, Thomas Bertsch, Carmen Clapp, Jakob Triebel
Journal: Front Endocrinol (Lausanne)
PubMed ID: 38742198
Doi: 10.3389/fendo.2024.1345996
Products & Services: Recombinant Proteins   
The Female-Biased General Odorant Binding Protein 2 of Displays Binding Affinity for Biologically Active Host Plant Volatiles
Authors: Jingjing Tu, Zehua Wang, Fan Yang, Han Liu, Guanghang Qiao, Aihuan Zhang, Shanning Wang
Journal: Biology (Basel)
PubMed ID: 38666886
Doi: 10.3390/biology13040274
Products & Services: Gene Synthesis   
Streptococcus pneumoniae endopeptidase O induces trained immunity and confers protection against various pathogenic infections
Authors: Wenlong Xu, Yuan Yuan, Zhaoche Shu, Ting Guo, Bichen Liu, Jiangming Xiao, Lian Li, Yibin Yin, Xuemei Zhang
Journal: Clin Immunol
PubMed ID: 38663493
Doi: 10.1016/j.clim.2024.110226
Products & Services: Molecular Biology Reagents   
P66 is a bacterial mimic of CD47 that binds the anti-phagocytic receptor SIRPα and facilitates macrophage evasion by
Authors: Michal Caspi Tal, Paige S Hansen, Haley A Ogasawara, Qingying Feng, Regan F Volk, Brandon Lee, Sara E Casebeer, Grace S Blacker, Maia Shoham, Sarah D Galloway, Anne L Sapiro, Beth Hayes, Laughing Bear Torrez Dulgeroff, Tal Raveh, Venkata Raveendra Pothineni, Hari-Hara Sk Potula, Jayakumar Rajadas, Effie E Bastounis, Seemay Chou, William H Robinson, Jenifer Coburn, Irving L Weissman, Balyn W Zaro
Journal: biorxiv
PubMed ID: 38746193
Doi: 10.1101/2024.04.29.591704
Mechanosensitive channel MscL gating transitions coupling with constriction point shift
Authors: Mingfeng Zhang, Siyang Tang, Xiaomin Wang, Sanhua Fang, Yuezhou Li
Journal: Protein Sci
PubMed ID: 38501596
Doi: 10.1002/pro.4965
An Omicron-specific, self-amplifying mRNA booster vaccine for COVID-19: a phase 2/3 randomized trial
Authors: Amit Saraf, Rohan Gurjar, Swarnendu Kaviraj, Aishwarya Kulkarni, Durgesh Kumar, Ruta Kulkarni, Rashmi Virkar, Jayashri Krishnan, Anjali Yadav, Ekta Baranwal, Ajay Singh, Arjun Raghuwanshi, Praveen Agarwal, Laxman Savergave, Sanjay Singh; GEMCOVAC-OM Study Investigators
Journal: nature medicine
PubMed ID: 38637636
Doi: 10.1038/s41591-024-02955-2
Products & Services: Serology SARS-Cov-2 detection kits   
Engineering allorejection-resistant CAR-NKT cells from hematopoietic stem cells for off-the-shelf cancer immunotherapy
Authors: Yan-Ruide Li, Yang Zhou 1, Jiaji Yu, Yichen Zhu, Derek Lee, Enbo Zhu, Zhe Li, Yu Jeong Kim, Kuangyi Zhou, Ying Fang, Zibai Lyu, Yuning Chen, Yanxin Tian, Jie Huang, Xinjian Cen, Tiffany Husman, Jae Min Cho, Tzung Hsiai, Jin J Zhou, Pin Wang, Benjamin R Puliafito, Sarah M Larson, Lili Yang
Journal: Molecular Therapy
PubMed ID: 38584391
Doi: 10.1016/j.ymthe.2024.04.005
Products & Services: Gene Synthesis   

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