Multiple iterations of chimeric antigen receptors (CARs) have been developed， mainly focusing on intracellular signaling modules. However， the effect of non-signaling extracellular modules on the expansion and therapeutic efficacy of CARs remains largely undefined.
Multiple iterations of chimeric antigen receptors (CARs) have been developed， mainly focusing on intracellular signaling modules. However， the effect of non-signaling extracellular modules on the expansion and therapeutic efficacy of CARs remains largely undefined.
