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Identification and Characterization of the First Cathelicidin from Sea Snakes with Potent Antimicrobial and Anti-inflammatory Activity and Special Mechanism.

J. Biol. Chem.. 2015; 
WeiLin,GaoJiuxiang,ZhangShumin,WuSijin,XieZeping,LingGuiying,KuangYi-Qun,YangYongliang,YuHaining,WangYi
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Cellular Analysis The ability of Hc-CATH to neutralize LPS was measured using a quantitative chromogenic limulus amebocyte lysate (LAL) method with a ToxinSensorTM chromogenic LAL endotoxin assay kit (GenScript, Nanjing, China). Get A Quote

摘要

the Jiangsu Key Laboratory of Infection and Immunity, Institutes of Biology and Medical Sciences, Soochow University, Suzhou, Jiangsu 215123, China.,the Department of Bioscience and Biotechnology, Dalian University of Technology, Dalian, Liaoning 116023, China.,the Binzhou Medical University of Pharmaceutical College, Yantai, Shandong 264003, China.,the Department of Bioscience and Biotechnology, Dalian University of Technology, Dalian, Liaoning 116023, China.,the Binzhou Medical University of Pharmaceutical College, Yantai, Shandong 264003, China.,the Cancer Immunology and Immunotherapy Center, Affiliated Hospital of Guiyang Medical College, Guiyang, Guizho... More

关键词

Hc-CATH,Hydrophis cyanocinctus,anti-inflammatory,antibiotics,antimicrobial peptide (AMP),cathelicidin,infection,inflammation,innate immu