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Synthetic Antibodies neutralize SARS-CoV-2 infection of mammalian cells

Clinical Trial. 2020-06; 
Feng-Cai Zhu , Yu-Hua Li , Xu-Hua Guan , Li-Hua Hou , Wen-Juan Wang , Jing-Xin Li , Shi-Po Wu , Bu-Sen Wang , Zhao Wang , Lei Wang , Si-Yue Jia , Hu-Dachuan Jiang , Ling Wang , Tao Jiang , Yi Hu , Jin-Bo Gou , Sha-Bei Xu , Jun-Jie Xu, Xue-Wen Wang, Wei Wang , Wei Chen
Products/Services Used Details Operation
Gene Synthesis synthesized by Genscript. cDNAencoding human ACE2 was obtained from MGC clone 47598. Get A Quote

摘要

Background: A vaccine to protect against COVID-19 is urgently needed. We aimed to assess the safety, tolerability, and immunogenicity of a recombinant adenovirus type-5 (Ad5) vectored COVID-19 vaccine expressing the spike glycoprotein of a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) strain.

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